no code implementations • 7 Feb 2017 • Ruilin Li, Martin G. Frasch, Hau-Tieng Wu
There is a need for affordable, widely deployable maternal-fetal ECG monitors to improve maternal and fetal health during pregnancy and delivery.
1 code implementation • 24 Aug 2018 • Martin G. Frasch, Chao Shen, Hau-Tieng Wu, Alexander Mueller, Emily Neuhaus, Raphael A. Bernier, Dana Kamara, Theodore P. Beauchaine
High-frequency heart rate variability (HRV) has identified parasympathetic nervous system alterations in autism spectrum disorder (ASD).
Quantitative Methods Neurons and Cognition
no code implementations • 27 Aug 2018 • Yu-Ting Lin, Yu-Lun Lo, Chen-Yun Lin, Hau-Tieng Wu, Martin G. Frasch
However, in this setup the data calibration issue is often not discussed and, rather, implicitly assumed, while the clinical monitors might not be designed for the data analysis purpose.
no code implementations • 1 Jan 2019 • Paula Desplats, Ashley M. Gutierrez, Marta C. Antonelli, Martin G. Frasch
We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding of this fundamental process.
no code implementations • 8 Sep 2019 • Martin G. Frasch, Byung-Jun Yoon, Dario-Lucas Helbing, Gal Snir, Marta C. Antonelli, Reinhard Bauer
Fetal neuroinflammation and prenatal stress (PS) may contribute to lifelong neurological disabilities.
no code implementations • 22 Jan 2020 • Martin G. Frasch
Heart rate variability (HRV) has been studied for over 50 years, yet an integrative concept is missing on what HRV's mathematical properties represent physiologically.
no code implementations • 10 Feb 2020 • Aude Castel, Patrick Burns, Colin Wakefield, Keven. J. Jean, Yael S. Frank, Mingju Cao, Andre Desrochers, Gilles Fecteau, Christophe Faure, Christophe L. Herry, Martin G. Frasch
We evaluated the effect of vagus nerve stimulation (VNS) on vagus nerve electroneurogram (VENG) and the systemic inflammatory response induced by a high dose of LPS in neonatal piglets to mimic late-onset neonatal sepsis.
no code implementations • 21 Feb 2020 • Martin G. Frasch, Bernd Walter, Christophe L. Herry, Reinhard Bauer
Ischemic brain injuries are frequent and difficult to detect reliably or early.
no code implementations • 24 Feb 2020 • Martin G. Frasch, Dino A. Giussani
Chronic fetal hypoxia and infection are examples of adverse conditions during complicated pregnancy, which impact cardiac myogenesis and increase the lifetime risk of heart disease.
no code implementations • 27 May 2020 • Aude Castel, Yael Frank, John Feltner, Floyd Karp, Catherine Albright, Martin G. Frasch
Background: Studies about the feasibility of monitoring fetal electroencephalogram (fEEG) during labor began in the early 1940s.
no code implementations • 19 Aug 2020 • Aude Castel, Patrick M. Burns, Javier Benito, Hai L. Liu, Shikha Kuthiala, Lucien D. Durosier, Yael S. Frank, Mingju Cao, Marilène Paquet, Gilles Fecteau, André Desrochers, Martin G. Frasch
Conclusions: This study describes a new surgical procedure allowing to record and manipulate chronically the vagus nerve activity in an animal model of human pregnancy.
2 code implementations • 3 Nov 2020 • Pritam Sarkar, Silvia Lobmaier, Bibiana Fabre, Diego González, Alexander Mueller, Martin G. Frasch, Marta C. Antonelli, Ali Etemad
Our DL models accurately detect the chronic stress exposure group (AUROC=0. 982+/-0. 002), the individual psychological stress score (R2=0. 943+/-0. 009) and FSI at 34 weeks of gestation (R2=0. 946+/-0. 013), as well as the maternal hair cortisol at birth reflecting chronic stress exposure (0. 931+/-0. 006).
no code implementations • 28 Feb 2021 • Martin G. Frasch, Bernd Walter, Christoph Anders, Reinhard Bauer
We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states.
no code implementations • 26 May 2021 • Peter Zimmermann, Marta C. Antonelli, Ritika Sharma, Alexander Müller, Camilla Zelgert, Bibiana Fabre, Natasha Wenzel, Hau-Tieng Wu, Martin G. Frasch, Silvia M. Lobmaier
What is the influence of chronic maternal prenatal stress (PS) on fetal iron homeostasis?
no code implementations • 1 Jun 2021 • Martin G. Frasch, Shadrian B. Strong, David Nilosek, Joshua Leaverton, Barry S. Schifrin
Ultimately, such a system could enable a physician to timely respond during labor and prevent adverse outcomes.
no code implementations • 3 Jun 2021 • Francesco Cerritelli, Martin G. Frasch, Marta C. Antonelli, Chiara Viglione, Stefano Vecchi, Marco Chiera, Andrea Manzotti
In addition, this paper will focus on which factors (i. e. fetal characteristics and behaviors, maternal lifestyle and pathologies, placental health and dysfunction, labor, incubator conditions, and drug exposure) may have an impact on the development of the vagus during the above-mentioned "critical window" and how.
no code implementations • 27 Mar 2022 • Mingju Cao, Shikha Kuthiala, Keven Jason Jean, Hai Lun Liu, Marc Courchesne, Karen Nygard, Patrick Burns, André Desrochers, Gilles Fecteau, Christophe Faure, Martin G. Frasch
Under conditions of moderate fetal inflammation, this is related to higher levels of gut inflammation; the efferent VNS reduces the systemic inflammatory response as well as restores both the levels of glucose and terminal ileum inflammation, but not the insulin levels.
no code implementations • 19 Dec 2022 • Marc Courchesne, Colin Wakefield, Karen Nygard, Patrick Burns, Gilles Fecteau, Andre Desrochers, Mingju Cao, Martin G. Frasch
The efferent and afferent effects of the vagus nerve on the developing brain have remained enigmatic.
no code implementations • 3 Oct 2023 • Martin G. Frasch
From the developmental neuroscience perspective, I present evidence for the central role of metabolically, rather than prediction-error-optimized neural architecture search (NAS).