1 code implementation • 6 Jun 2024 • Shruthi Bannur, Kenza Bouzid, Daniel C. Castro, Anton Schwaighofer, Sam Bond-Taylor, Maximilian Ilse, Fernando Pérez-García, Valentina Salvatelli, Harshita Sharma, Felix Meissen, Mercy Ranjit, Shaury Srivastav, Julia Gong, Fabian Falck, Ozan Oktay, Anja Thieme, Matthew P. Lungren, Maria Teodora Wetscherek, Javier Alvarez-Valle, Stephanie L. Hyland
Radiology reporting is a complex task that requires detailed image understanding, integration of multiple inputs, including comparison with prior imaging, and precise language generation.
no code implementations • 8 May 2024 • Anja Thieme, Abhijith Rajamohan, Benjamin Cooper, Heather Groombridge, Robert Simister, Barney Wong, Nicholas Woznitza, Mark Ames Pinnock, Maria Teodora Wetscherek, Cecily Morrison, Hannah Richardson, Fernando Pérez-García, Stephanie L. Hyland, Shruthi Bannur, Daniel C. Castro, Kenza Bouzid, Anton Schwaighofer, Mercy Ranjit, Harshita Sharma, Matthew P. Lungren, Ozan Oktay, Javier Alvarez-Valle, Aditya Nori, Stephen Harris, Joseph Jacob
Nasogastric tubes (NGTs) are feeding tubes that are inserted through the nose into the stomach to deliver nutrition or medication.
no code implementations • 12 Mar 2024 • Juan Manuel Zambrano Chaves, Shih-Cheng Huang, Yanbo Xu, Hanwen Xu, Naoto Usuyama, Sheng Zhang, Fei Wang, Yujia Xie, Mahmoud Khademi, ZiYi Yang, Hany Awadalla, Julia Gong, Houdong Hu, Jianwei Yang, Chunyuan Li, Jianfeng Gao, Yu Gu, Cliff Wong, Mu Wei, Tristan Naumann, Muhao Chen, Matthew P. Lungren, Akshay Chaudhari, Serena Yeung-Levy, Curtis P. Langlotz, Sheng Wang, Hoifung Poon
Frontier general-domain models such as GPT-4V still have significant performance gaps in multimodal biomedical applications.
no code implementations • 19 Jan 2024 • Fernando Pérez-García, Harshita Sharma, Sam Bond-Taylor, Kenza Bouzid, Valentina Salvatelli, Maximilian Ilse, Shruthi Bannur, Daniel C. Castro, Anton Schwaighofer, Matthew P. Lungren, Maria Wetscherek, Noel Codella, Stephanie L. Hyland, Javier Alvarez-Valle, Ozan Oktay
We introduce RAD-DINO, a biomedical image encoder pre-trained solely on unimodal biomedical imaging data that obtains similar or greater performance than state-of-the-art biomedical language supervised models on a diverse range of benchmarks.
no code implementations • 20 Dec 2023 • Fernando Pérez-García, Sam Bond-Taylor, Pedro P. Sanchez, Boris van Breugel, Daniel C. Castro, Harshita Sharma, Valentina Salvatelli, Maria T. A. Wetscherek, Hannah Richardson, Matthew P. Lungren, Aditya Nori, Javier Alvarez-Valle, Ozan Oktay, Maximilian Ilse
Biomedical imaging datasets are often small and biased, meaning that real-world performance of predictive models can be substantially lower than expected from internal testing.
1 code implementation • 23 Nov 2023 • Asma Ben Abacha, Alberto Santamaria-Pang, Ho Hin Lee, Jameson Merkow, Qin Cai, Surya Teja Devarakonda, Abdullah Islam, Julia Gong, Matthew P. Lungren, Thomas Lin, Noel C Codella, Ivan Tarapov
The increasing use of medical imaging in healthcare settings presents a significant challenge due to the increasing workload for radiologists, yet it also offers opportunity for enhancing healthcare outcomes if effectively leveraged.
no code implementations • 22 Nov 2023 • Stephanie L. Hyland, Shruthi Bannur, Kenza Bouzid, Daniel C. Castro, Mercy Ranjit, Anton Schwaighofer, Fernando Pérez-García, Valentina Salvatelli, Shaury Srivastav, Anja Thieme, Noel Codella, Matthew P. Lungren, Maria Teodora Wetscherek, Ozan Oktay, Javier Alvarez-Valle
We present a radiology-specific multimodal model for the task for generating radiological reports from chest X-rays (CXRs).
no code implementations • 23 Oct 2023 • Qianchu Liu, Stephanie Hyland, Shruthi Bannur, Kenza Bouzid, Daniel C. Castro, Maria Teodora Wetscherek, Robert Tinn, Harshita Sharma, Fernando Pérez-García, Anton Schwaighofer, Pranav Rajpurkar, Sameer Tajdin Khanna, Hoifung Poon, Naoto Usuyama, Anja Thieme, Aditya V. Nori, Matthew P. Lungren, Ozan Oktay, Javier Alvarez-Valle
In this paper, we focus on assessing the performance of GPT-4, the most capable LLM so far, on the text-based applications for radiology reports, comparing against state-of-the-art (SOTA) radiology-specific models.
no code implementations • 16 Oct 2023 • Yu Gu, Jianwei Yang, Naoto Usuyama, Chunyuan Li, Sheng Zhang, Matthew P. Lungren, Jianfeng Gao, Hoifung Poon
In a comprehensive battery of tests on counterfactual medical image generation, BiomedJourney substantially outperforms prior state-of-the-art methods in instruction image editing and medical image generation such as InstructPix2Pix and RoentGen.
3 code implementations • 2 Mar 2023 • Sheng Zhang, Yanbo Xu, Naoto Usuyama, Hanwen Xu, Jaspreet Bagga, Robert Tinn, Sam Preston, Rajesh Rao, Mu Wei, Naveen Valluri, Cliff Wong, Andrea Tupini, Yu Wang, Matt Mazzola, Swadheen Shukla, Lars Liden, Jianfeng Gao, Matthew P. Lungren, Tristan Naumann, Sheng Wang, Hoifung Poon
Therefore, training an effective generalist biomedical model requires high-quality multimodal data, such as parallel image-text pairs.
Ranked #3 on Medical Visual Question Answering on SLAKE-English
1 code implementation • 8 Feb 2023 • Yuhui Zhang, Shih-Cheng Huang, Zhengping Zhou, Matthew P. Lungren, Serena Yeung
Given the prevalence of 3D medical imaging technologies such as MRI and CT that are widely used in diagnosing and treating diverse diseases, 3D segmentation is one of the fundamental tasks of medical image analysis.
no code implementations • CVPR 2023 • Shruthi Bannur, Stephanie Hyland, Qianchu Liu, Fernando Pérez-García, Maximilian Ilse, Daniel C. Castro, Benedikt Boecking, Harshita Sharma, Kenza Bouzid, Anja Thieme, Anton Schwaighofer, Maria Wetscherek, Matthew P. Lungren, Aditya Nori, Javier Alvarez-Valle, Ozan Oktay
Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical notes commonly refer to prior images.
1 code implementation • Nature Machine Intelligence 2022 • Adriel Saporta, Xiaotong Gui, Ashwin Agrawal, Anuj Pareek, Steven Q. H. Truong, Chanh D. T. Nguyen, Van-Doan Ngo, Jayne Seekins, Francis G. Blankenberg, Andrew Y. Ng, Matthew P. Lungren, Pranav Rajpurkar
Saliency methods, which produce heat maps that highlight the areas of the medical image that influence model prediction, are often presented to clinicians as an aid in diagnostic decision-making.
1 code implementation • CVPR 2024 • Yuyin Zhou, Xianhang Li, Fengze Liu, Qingyue Wei, Xuxi Chen, Lequan Yu, Cihang Xie, Matthew P. Lungren, Lei Xing
Extensive experiments demonstrate that our method effectively mitigates the challenges of noisy labels, often necessitating few to no validation samples, and is well generalized to other tasks such as image segmentation.
Ranked #8 on Image Classification on Clothing1M (using clean data) (using extra training data)
no code implementations • 23 Nov 2021 • Yuyin Zhou, Shih-Cheng Huang, Jason Alan Fries, Alaa Youssef, Timothy J. Amrhein, Marcello Chang, Imon Banerjee, Daniel Rubin, Lei Xing, Nigam Shah, Matthew P. Lungren
Despite the routine use of electronic health record (EHR) data by radiologists to contextualize clinical history and inform image interpretation, the majority of deep learning architectures for medical imaging are unimodal, i. e., they only learn features from pixel-level information.
no code implementations • 9 Nov 2021 • Michael Fitzke, Conrad Stack, Andre Dourson, Rodrigo M. B. Santana, Diane Wilson, Lisa Ziemer, Arjun Soin, Matthew P. Lungren, Paul Fisher, Mark Parkinson
This work describes the development and real-world deployment of a deep learning-based AI system for evaluating canine and feline radiographs across a broad range of findings and abnormalities.
no code implementations • 23 Sep 2021 • Ruiyang Zhao, Yuxin Zhang, Burhaneddin Yaman, Matthew P. Lungren, Michael S. Hansen
Deep learning techniques have emerged as a promising approach to highly accelerated MRI.
1 code implementation • 8 Sep 2021 • Ruiyang Zhao, Burhaneddin Yaman, Yuxin Zhang, Russell Stewart, Austin Dixon, Florian Knoll, Zhengnan Huang, Yvonne W. Lui, Michael S. Hansen, Matthew P. Lungren
Improving speed and image quality of Magnetic Resonance Imaging (MRI) via novel reconstruction approaches remains one of the highest impact applications for deep learning in medical imaging.
no code implementations • 17 Aug 2021 • Michael Fitzke, Derick Whitley, Wilson Yau, Fernando Rodrigues Jr, Vladimir Fadeev, Cindy Bacmeister, Chris Carter, Jeffrey Edwards, Matthew P. Lungren, Mark Parkinson
Approach: Multiple state-of-the-art deep learning techniques for histopathology image classification and mitotic figure detection were used in the development of OncoPetNet.
1 code implementation • 28 Jun 2021 • Saahil Jain, Ashwin Agrawal, Adriel Saporta, Steven QH Truong, Du Nguyen Duong, Tan Bui, Pierre Chambon, Yuhao Zhang, Matthew P. Lungren, Andrew Y. Ng, Curtis P. Langlotz, Pranav Rajpurkar
We release a development dataset, which contains board-certified radiologist annotations for 500 radiology reports from the MIMIC-CXR dataset (14, 579 entities and 10, 889 relations), and a test dataset, which contains two independent sets of board-certified radiologist annotations for 100 radiology reports split equally across the MIMIC-CXR and CheXpert datasets.
1 code implementation • 23 Jun 2021 • Grant Duffy, Paul P Cheng, Neal Yuan, Bryan He, Alan C. Kwan, Matthew J. Shun-Shin, Kevin M. Alexander, Joseph Ebinger, Matthew P. Lungren, Florian Rader, David H. Liang, Ingela Schnittger, Euan A. Ashley, James Y. Zou, Jignesh Patel, Ronald Witteles, Susan Cheng, David Ouyang
Left ventricular hypertrophy (LVH) results from chronic remodeling caused by a broad range of systemic and cardiovascular disease including hypertension, aortic stenosis, hypertrophic cardiomyopathy, and cardiac amyloidosis.
1 code implementation • 7 May 2021 • Christian Garbin, Pranav Rajpurkar, Jeremy Irvin, Matthew P. Lungren, Oge Marques
Following the structured format of Datasheets for Datasets, this paper expands on the original CheXpert paper and other sources to show the critical role played by radiologists in the creation of reliable labels and to describe the different aspects of the dataset composition in detail.
1 code implementation • 23 Feb 2021 • Saahil Jain, Akshay Smit, Steven QH Truong, Chanh DT Nguyen, Minh-Thanh Huynh, Mudit Jain, Victoria A. Young, Andrew Y. Ng, Matthew P. Lungren, Pranav Rajpurkar
We also find that VisualCheXbert better agrees with radiologists labeling chest X-ray images than do radiologists labeling the corresponding radiology reports by an average F1 score across several medical conditions of between 0. 12 (95% CI 0. 09, 0. 15) and 0. 21 (95% CI 0. 18, 0. 24).
2 code implementations • 18 Feb 2021 • Joseph Paul Cohen, Rupert Brooks, Sovann En, Evan Zucker, Anuj Pareek, Matthew P. Lungren, Akshay Chaudhari
We also found that the Latent Shift explanation allows a user to have more confidence in true positive predictions compared to traditional approaches (0. 15$\pm$0. 95 in a 5 point scale with p=0. 01) with only a small increase in false positive predictions (0. 04$\pm$1. 06 with p=0. 57).
1 code implementation • 17 Feb 2021 • Pranav Rajpurkar, Anirudh Joshi, Anuj Pareek, Andrew Y. Ng, Matthew P. Lungren
Recent advances in training deep learning models have demonstrated the potential to provide accurate chest X-ray interpretation and increase access to radiology expertise.
2 code implementations • ICCV 2021 • Shih-Cheng Huang, Liyue Shen, Matthew P. Lungren, Serena Yeung
In recent years, the growing number of medical imaging studies is placing an ever-increasing burden on radiologists.
1 code implementation • 13 Jul 2020 • Nick A. Phillips, Pranav Rajpurkar, Mark Sabini, Rayan Krishnan, Sharon Zhou, Anuj Pareek, Nguyet Minh Phu, Chris Wang, Mudit Jain, Nguyen Duong Du, Steven QH Truong, Andrew Y. Ng, Matthew P. Lungren
We introduce CheXphoto, a dataset of smartphone photos and synthetic photographic transformations of chest x-rays sampled from the CheXpert dataset.
6 code implementations • 20 Apr 2020 • Akshay Smit, Saahil Jain, Pranav Rajpurkar, Anuj Pareek, Andrew Y. Ng, Matthew P. Lungren
The extraction of labels from radiology text reports enables large-scale training of medical imaging models.
no code implementations • 17 Mar 2020 • Sarah M. Hooper, Jared A. Dunnmon, Matthew P. Lungren, Sanjiv Sam Gambhir, Christopher Ré, Adam S. Wang, Bhavik N. Patel
We then show that the trained model is robust to reduced tube current and fewer projections, with the AUROC dropping only 0. 65% for images acquired with a 16x reduction in tube current and 0. 22% for images acquired with 8x fewer projections.
no code implementations • 26 Feb 2020 • Pranav Rajpurkar, Anirudh Joshi, Anuj Pareek, Phil Chen, Amirhossein Kiani, Jeremy Irvin, Andrew Y. Ng, Matthew P. Lungren
First, we find that the top 10 chest x-ray models on the CheXpert competition achieve an average AUC of 0. 851 on the task of detecting TB on two public TB datasets without fine-tuning or including the TB labels in training data.
12 code implementations • 21 Jan 2019 • Jeremy Irvin, Pranav Rajpurkar, Michael Ko, Yifan Yu, Silviana Ciurea-Ilcus, Chris Chute, Henrik Marklund, Behzad Haghgoo, Robyn Ball, Katie Shpanskaya, Jayne Seekins, David A. Mong, Safwan S. Halabi, Jesse K. Sandberg, Ricky Jones, David B. Larson, Curtis P. Langlotz, Bhavik N. Patel, Matthew P. Lungren, Andrew Y. Ng
On a validation set of 200 chest radiographic studies which were manually annotated by 3 board-certified radiologists, we find that different uncertainty approaches are useful for different pathologies.
Ranked #96 on Multi-Label Classification on CheXpert
1 code implementation • 21 Jan 2019 • Alistair E. W. Johnson, Tom J. Pollard, Nathaniel R. Greenbaum, Matthew P. Lungren, Chih-ying Deng, Yifan Peng, Zhiyong Lu, Roger G. Mark, Seth J. Berkowitz, Steven Horng
Chest radiography is an extremely powerful imaging modality, allowing for a detailed inspection of a patient's thorax, but requiring specialized training for proper interpretation.
1 code implementation • Medicine 2018 • Nicholas Bien, Pranav Rajpurkar, Robyn L. Ball, Jeremy Irvin, Allison Park, Erik Jones, Michael Bereket, Bhavik N. Patel, Kristen W. Yeom, Katie Shpanskaya, Safwan Halabi, Evan Zucker, Gary Fanton, Derek F. Amanatullah, Christopher F. Beaulieu, Geoffrey M. Riley, Russell J. Stewart, Francis G. Blankenberg, David B. Larson, Ricky H. Jones, Curtis P. Langlotz, Andrew Y. Ng, Matthew P. Lungren
Magnetic resonance imaging (MRI) of the knee is the preferred method for diagnosing knee injuries.
Ranked #1 on Multi-Label Classification on MRNet
11 code implementations • 11 Dec 2017 • Pranav Rajpurkar, Jeremy Irvin, Aarti Bagul, Daisy Ding, Tony Duan, Hershel Mehta, Brandon Yang, Kaylie Zhu, Dillon Laird, Robyn L. Ball, Curtis Langlotz, Katie Shpanskaya, Matthew P. Lungren, Andrew Y. Ng
To evaluate models robustly and to get an estimate of radiologist performance, we collect additional labels from six board-certified Stanford radiologists on the test set, consisting of 207 musculoskeletal studies.
46 code implementations • 14 Nov 2017 • Pranav Rajpurkar, Jeremy Irvin, Kaylie Zhu, Brandon Yang, Hershel Mehta, Tony Duan, Daisy Ding, Aarti Bagul, Curtis Langlotz, Katie Shpanskaya, Matthew P. Lungren, Andrew Y. Ng
We develop an algorithm that can detect pneumonia from chest X-rays at a level exceeding practicing radiologists.
Ranked #3 on Pneumonia Detection on ChestX-ray14