no code implementations • 30 Jul 2024 • Monica Isgut, Andrew Hornback, Yunan Luo, Asma Khimani, Neha Jain, May D. Wang
While our model did not demonstrate improved performance over the baseline, we discovered 248 (<1%) statistically significant gene-by-gene and gene-by-environment interactions out of the ~53. 6k possible feature pairs, the most contributory of which included rs6001930 (MKL1) and rs889312 (MAP3K1), with age and menopause being the most heavily interacting non-genetic risk factors.
1 code implementation • 5 May 2024 • Wenqi Shi, ran Xu, Yuchen Zhuang, Yue Yu, Haotian Sun, Hang Wu, Carl Yang, May D. Wang
Faced with the challenges of balancing model performance, computational resources, and data privacy, MedAdapter provides an efficient, privacy-preserving, cost-effective, and transparent solution for adapting LLMs to the biomedical domain.
1 code implementation • 29 Apr 2024 • ran Xu, Wenqi Shi, Yue Yu, Yuchen Zhuang, Yanqiao Zhu, May D. Wang, Joyce C. Ho, Chao Zhang, Carl Yang
Developing effective biomedical retrieval models is important for excelling at knowledge-intensive biomedical tasks but still challenging due to the deficiency of sufficient publicly annotated biomedical data and computational resources.
1 code implementation • 25 Feb 2024 • ran Xu, Wenqi Shi, Yue Yu, Yuchen Zhuang, Bowen Jin, May D. Wang, Joyce C. Ho, Carl Yang
We present RAM-EHR, a Retrieval AugMentation pipeline to improve clinical predictions on Electronic Health Records (EHRs).
1 code implementation • 13 Jan 2024 • Wenqi Shi, ran Xu, Yuchen Zhuang, Yue Yu, Jieyu Zhang, Hang Wu, Yuanda Zhu, Joyce Ho, Carl Yang, May D. Wang
Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving.
no code implementations • 23 Dec 2021 • Felipe Giuste, Wenqi Shi, Yuanda Zhu, Tarun Naren, Monica Isgut, Ying Sha, Li Tong, Mitali Gupte, May D. Wang
This systematic review examines the use of Explainable Artificial Intelligence (XAI) during the pandemic and how its use could overcome barriers to real-world success.
no code implementations • 22 Sep 2020 • Yuanda Zhu, Ying Sha, Hang Wu, Mai Li, Ryan A. Hoffman, May D. Wang
The sequence of clinical codes on the death report is named as causal chain of death, coded in the tenth revision of International Statistical Classification of Diseases (ICD-10); in line with the ICD-9-CM Official Guidelines for Coding and Reporting, the priority-ordered clinical conditions on the discharge record are coded in ICD-9.
no code implementations • 12 Oct 2019 • Yundong Zhang, Hang Wu, Huiye Liu, Li Tong, May D. Wang
In this study, we investigated model robustness to dataset bias using three large-scale Chest X-ray datasets: first, we assessed the dataset bias using vanilla training baseline; second, we proposed a novel multi-source domain generalization model by (a) designing a new bias-regularized loss function; and (b) synthesizing new data for domain augmentation.
no code implementations • 6 May 2017 • Hamid Reza Hassanzadeh, Ying Sha, May D. Wang
Multiple cause-of-death data provides a valuable source of information that can be used to enhance health standards by predicting health related trajectories in societies with large populations.
no code implementations • 4 May 2017 • Hamid Reza Hassanzadeh, Pushkar Kolhe, Charles L. Isbell, May D. Wang
A number of high-throughput technologies have recently emerged that try to quantify the affinity between proteins and DNA motifs.
no code implementations • 17 Nov 2016 • Hamid Reza Hassanzadeh, John H. Phan, May D. Wang
Despite the wealth of information available in expression profiles of cancer tumors, fulfilling the aforementioned objective remains a big challenge, for the most part, due to the paucity of data samples compared to the high dimension of the expression profiles.
1 code implementation • 17 Nov 2016 • Hamid Reza Hassanzadeh, May D. Wang
To the best of our knowledge, this is the most accurate pipeline that can predict binding specificities of DNA sequences from the data produced by high-throughput technologies through utilization of the power of deep learning for feature generation and positional dynamics modeling.
no code implementations • 29 Sep 2015 • Hamid Reza Hassanzadeh, John H. Phan, May D. Wang
The results of applying our method to three cancer datasets show the promise of semi-supervised learning for prediction of cancer survival.