diproperm: An R Package for the DiProPerm Test

no code implementations • 30 Aug 2020 • Andrew G. Allmon, J. S. Marron, Michael G. Hudgens

The direction-projection-permutation (DiProPerm) test was developed for testing the difference of two high-dimensional distributions induced by a binary linear classifier.

Post-randomization Biomarker Effect Modification in an HIV Vaccine Clinical Trial

1 code implementation • 9 Nov 2018 • Peter B. Gilbert, Bryan S. Blette, Bryan E. Shepherd, Michael G. Hudgens

While the HVTN 505 trial showed no overall efficacy of the tested vaccine to prevent HIV infection over placebo, previous studies, biological theories, and the finding that immune response markers strongly correlated with infection in vaccine recipients generated the hypothesis that a qualitative interaction occurred.

Applications

Randomization inference with general interference and censoring

1 code implementation • 6 Mar 2018 • Wen Wei Loh, Michael G. Hudgens, John D. Clemens, Mohammad Ali, Michael E. Emch

Permitting right censored outcomes is challenging because standard randomization-based tests of the null hypothesis of no treatment effect assume that whether an individual is censored does not depend on treatment.

Methodology

Causal Inference from Observational Studies with Clustered Interference

1 code implementation • 13 Nov 2017 • Brian G. Barkley, Michael G. Hudgens, John D. Clemens, Mohammad Ali, Michael E. Emch

Inverse probability-weighted estimators for these estimands are proposed.

Methodology