1 code implementation • 27 Aug 2024 • Yiqing Shen, Zan Chen, Michail Mamalakis, Yungeng Liu, Tianbin Li, Yanzhou Su, Junjun He, Pietro Liò, Yu Guang Wang
While large language models (LLMs) have achieved much progress in the domain of natural language processing, their potential in protein engineering remains largely unexplored.
1 code implementation • 8 Jun 2024 • Yiqing Shen, Zan Chen, Michail Mamalakis, Luhan He, Haiyang Xia, Tianbin Li, Yanzhou Su, Junjun He, Yu Guang Wang
The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding.
no code implementations • 29 May 2024 • Michail Mamalakis, Héloïse de Vareilles, Shun-Chin Jim Wu, Ingrid Agartz, Lynn Egeland Mørch-Johnsen, Jane Garrison, Jon Simons, Pietro Lio, John Suckling, Graham Murray
Techniques like adversarial learning, contrastive learning, diffusion denoising learning, and ordinary reconstruction learning have become standard, representing state-of-the-art methods extensively employed for fully training or pre-training networks across various vision tasks.
1 code implementation • 16 May 2024 • Michail Mamalakis, Antonios Mamalakis, Ingrid Agartz, Lynn Egeland Mørch-Johnsen, Graham Murray, John Suckling, Pietro Lio
In this study, for the first time, we propose a novel framework designed to enhance the explainability of deep networks, by maximizing both the accuracy and the comprehensibility of the explanations.
1 code implementation • 21 Dec 2023 • Yang Nan, Xiaodan Xing, Shiyi Wang, Zeyu Tang, Federico N Felder, Sheng Zhang, Roberta Eufrasia Ledda, Xiaoliu Ding, Ruiqi Yu, Weiping Liu, Feng Shi, Tianyang Sun, Zehong Cao, Minghui Zhang, Yun Gu, Hanxiao Zhang, Jian Gao, Pingyu Wang, Wen Tang, Pengxin Yu, Han Kang, Junqiang Chen, Xing Lu, Boyu Zhang, Michail Mamalakis, Francesco Prinzi, Gianluca Carlini, Lisa Cuneo, Abhirup Banerjee, Zhaohu Xing, Lei Zhu, Zacharia Mesbah, Dhruv Jain, Tsiry Mayet, Hongyu Yuan, Qing Lyu, Abdul Qayyum, Moona Mazher, Athol Wells, Simon LF Walsh, Guang Yang
The online validation set incorporated 52 HRCT scans from patients with fibrotic lung disease and the offline test set included 140 cases from fibrosis and COVID-19 patients.
1 code implementation • 2 Sep 2023 • Michail Mamalakis, Heloise de Vareilles, Atheer AI-Manea, Samantha C. Mitchell, Ingrid Arartz, Lynn Egeland Morch-Johnsen, Jane Garrison, Jon Simons, Pietro Lio, John Suckling, Graham Murray
The significant features identified in a representative subset of the dataset during the learning process of an artificial intelligence model are referred to as a 'global' explanation.
1 code implementation • 2 Sep 2023 • Michail Mamalakis, Sarah C. Macfarlane, Scott V. Notley, Annica K. B Gad, George Panoutsos
The method relies on fluorescence microscopy images showing the spatial organization of actin and vimentin filaments in normal and metastasizing single cells, using a combination of multi-attention channels network and global explainable techniques.
no code implementations • 8 Apr 2021 • Michail Mamalakis, Andrew J. Swift, Bart Vorselaars, Surajit Ray, Simonne Weeks, Weiping Ding, Richard H. Clayton, Louise S. Mackenzie, Abhirup Banerjee
The global pandemic of COVID-19 is continuing to have a significant effect on the well-being of global population, increasing the demand for rapid testing, diagnosis, and treatment.