no code implementations • 10 Jun 2024 • Mingtao Xia, Qijing Shen
In this paper, we propose a local squared Wasserstein-2 (W_2) method to solve the inverse problem of reconstructing models with uncertain latent variables or parameters.
no code implementations • 3 Jun 2024 • Mingtao Xia, Xiangting Li, Qijing Shen, Tom Chou
We analyze the Wasserstein distance ($W$-distance) between two probability distributions associated with two multidimensional jump-diffusion processes.
no code implementations • 8 Mar 2024 • Mingtao Xia, Tom Chou
We formulate a general, high-dimensional kinetic theory describing the internal state (such as gene expression or protein levels) of cells in a stochastically evolving population.
no code implementations • 21 Jan 2024 • Mingtao Xia, Xiangting Li, Qijing Shen, Tom Chou
We provide an analysis of the squared Wasserstein-2 ($W_2$) distance between two probability distributions associated with two stochastic differential equations (SDEs).
no code implementations • 28 Sep 2023 • Mingtao Xia, Xiangting Li, Qijing Shen, Tom Chou
Rapidly developing machine learning methods has stimulated research interest in computationally reconstructing differential equations (DEs) from observational data which may provide additional insight into underlying causative mechanisms.
no code implementations • 1 Mar 2023 • Mingtao Xia, Xiangting Li, Tom Chou
There has been renewed interest in understanding the mathematical structure of ecological population models that lead to overcompensation, the process by which a population recovers to a higher level after suffering a permanent increase in predation or harvesting.
1 code implementation • 6 Feb 2022 • Mingtao Xia, Lucas Böttcher, Tom Chou
We propose a solution to such problems by combining two classes of numerical methods: (i) adaptive spectral methods and (ii) physics-informed neural networks (PINNs).
1 code implementation • 29 Jul 2021 • Mingtao Xia, Lucas Böttcher, Tom Chou
Efficient testing and vaccination protocols are critical aspects of epidemic management.
no code implementations • 27 Mar 2020 • Mingtao Xia, Chris D. Greenman, Tom Chou
Existence and uniqueness of weak solutions to our 2+1-dimensional PDE model are proved, leading to the convergence of the discretized numerical solutions and allowing us to numerically compute the dynamics of cell population densities.
no code implementations • 18 Jun 2019 • Renaud Dessalles, Yunbei Pan, Mingtao Xia, Davide Maestrini, Maria R. D'Orsogna, Tom Chou
Using a mean-field approximation to the solution of a regulated birth-death-immigration model and a modification arising from sampling, we systematically quantify how TCR-dependent heterogeneities in immigration and proliferation rates affect the shape of clone abundance distributions (the number of different clones that are represented by a specific number of cells, or "clone counts").