Search Results for author: Mohit Kumar Jolly

Found 4 papers, 0 papers with code

Mathematical Modeling of Plasticity and Heterogeneity in EMT

no code implementations25 Jul 2019 Shubham Tripathi, Jianhua Xing, Herbert Levine, Mohit Kumar Jolly

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels.

Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response

no code implementations16 Apr 2019 Dongya Jia, Xuefei Li, Federico Bocci, Shubham Tripathi, Youyuan Deng, Mohit Kumar Jolly, Jose N. Onuchic, Herbert Levine

In this review, we first discuss recent efforts combining theoretical and experimental approaches to elucidate mechanisms underlying EMT multi-stability (i. e. the existence of multiple stable phenotypes during EMT) and the properties of hybrid E/M phenotypes.

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