Search Results for author: Nikos Makris

Found 26 papers, 5 papers with code

A Multimodal Deep Learning Approach for White Matter Shape Prediction in Diffusion MRI Tractography

no code implementations25 Apr 2025 Yui Lo, Yuqian Chen, Dongnan Liu, Leo Zekelman, Jarrett Rushmore, Yogesh Rathi, Nikos Makris, Alexandra J. Golby, Fan Zhang, Weidong Cai, Lauren J. O'Donnell

We propose Tract2Shape, a novel multimodal deep learning framework that leverages geometric (point cloud) and scalar (tabular) features to predict ten white matter tractography shape measures.

Diffusion MRI Dimensionality Reduction +1

DeepNuParc: A Novel Deep Clustering Framework for Fine-scale Parcellation of Brain Nuclei Using Diffusion MRI Tractography

1 code implementation10 Mar 2025 Haolin He, Ce Zhu, Le Zhang, Yipeng Liu, Xiao Xu, Yuqian Chen, Leo Zekelman, Jarrett Rushmore, Yogesh Rathi, Nikos Makris, Lauren J. O'Donnell, Fan Zhang

Diffusion MRI tractography is an advanced imaging technique that can estimate the brain's white matter structural connectivity to potentially reveal the topography of the nuclei of interest for studying its subdivisions.

Clustering Deep Clustering +2

TractShapeNet: Efficient Multi-Shape Learning with 3D Tractography Point Clouds

1 code implementation29 Oct 2024 Yui Lo, Yuqian Chen, Dongnan Liu, Jon Haitz Legarreta, Leo Zekelman, Fan Zhang, Jarrett Rushmore, Yogesh Rathi, Nikos Makris, Alexandra J. Golby, Weidong Cai, Lauren J. O'Donnell

In this work, we investigate the possibility of utilizing a deep learning model to compute shape measures of the brain's white matter connections.

Diffusion MRI

Deep multimodal saliency parcellation of cerebellar pathways: linking microstructure and individual function through explainable multitask learning

no code implementations21 Jul 2024 Ari Tchetchenian, Leo Zekelman, Yuqian Chen, Jarrett Rushmore, Fan Zhang, Edward H. Yeterian, Nikos Makris, Yogesh Rathi, Erik Meijering, Yang song, Lauren J. O'Donnell

We refer to our method as Deep Multimodal Saliency Parcellation (DeepMSP), as it computes the saliency of structural measures for predicting cognitive and motor functional performance, with these saliencies being applied to the task of parcellation.

Diffusion MRI

TractGraphFormer: Anatomically Informed Hybrid Graph CNN-Transformer Network for Classification from Diffusion MRI Tractography

no code implementations11 Jul 2024 Yuqian Chen, Fan Zhang, Meng Wang, Leo R. Zekelman, Suheyla Cetin-Karayumak, Tengfei Xue, Chaoyi Zhang, Yang song, Nikos Makris, Yogesh Rathi, Weidong Cai, Lauren J. O'Donnell

The proposed approach highlights the potential of integrating local anatomical information and global feature dependencies to improve prediction performance in machine learning with diffusion MRI tractography.

Diffusion MRI

A diffusion MRI tractography atlas for concurrent white matter mapping across Eastern and Western populations

no code implementations6 Apr 2024 Yijie Li, Wei zhang, Ye Wu, Li Yin, Ce Zhu, Yuqian Chen, Suheyla Cetin-Karayumak, Kang Ik K Cho, Leo R. Zekelman, Jarrett Rushmore, Yogesh Rathi, Nikos Makris, Lauren J. O'Donnell, Fan Zhang

However, a comprehensive investigation into WM fiber tracts between Eastern and Western populations is challenged due to the lack of a cross-population WM atlas and the large site-specific variability of dMRI data.

Diffusion MRI

A Novel Deep Clustering Framework for Fine-Scale Parcellation of Amygdala Using dMRI Tractography

no code implementations25 Nov 2023 Haolin He, Ce Zhu, Le Zhang, Yipeng Liu, Xiao Xu, Yuqian Chen, Leo Zekelman, Jarrett Rushmore, Yogesh Rathi, Nikos Makris, Lauren J. O'Donnell, Fan Zhang

The amygdala plays a vital role in emotional processing and exhibits structural diversity that necessitates fine-scale parcellation for a comprehensive understanding of its anatomico-functional correlations.

Clustering Deep Clustering +3

TractCloud: Registration-free tractography parcellation with a novel local-global streamline point cloud representation

no code implementations18 Jul 2023 Tengfei Xue, Yuqian Chen, Chaoyi Zhang, Alexandra J. Golby, Nikos Makris, Yogesh Rathi, Weidong Cai, Fan Zhang, Lauren J. O'Donnell

TractCloud achieves efficient and consistent whole-brain white matter parcellation across the lifespan (from neonates to elderly subjects, including brain tumor patients) without the need for registration.

Anatomy Diffusion MRI

TractGeoNet: A geometric deep learning framework for pointwise analysis of tract microstructure to predict language assessment performance

no code implementations8 Jul 2023 Yuqian Chen, Leo R. Zekelman, Chaoyi Zhang, Tengfei Xue, Yang song, Nikos Makris, Yogesh Rathi, Alexandra J. Golby, Weidong Cai, Fan Zhang, Lauren J. O'Donnell

We evaluate the effectiveness of the proposed method by predicting individual performance on two neuropsychological assessments of language using a dataset of 20 association white matter fiber tracts from 806 subjects from the Human Connectome Project.

regression

Fiber Tract Shape Measures Inform Prediction of Non-Imaging Phenotypes

no code implementations16 Mar 2023 Wan Liu, Yuqian Chen, Chuyang Ye, Nikos Makris, Yogesh Rathi, Weidong Cai, Fan Zhang, Lauren J. O'Donnell

In this paper, we investigate the potential of fiber tract shape features for predicting non-imaging phenotypes, both individually and in combination with traditional features.

Diffusion MRI Prediction

TractGraphCNN: anatomically informed graph CNN for classification using diffusion MRI tractography

no code implementations5 Jan 2023 Yuqian Chen, Fan Zhang, Leo R. Zekelman, Tengfei Xue, Chaoyi Zhang, Yang song, Nikos Makris, Yogesh Rathi, Weidong Cai, Lauren J. O'Donnell

This work shows the potential of incorporating anatomical information, especially known anatomical similarities between input features, to guide convolutions in neural networks.

Diffusion MRI

Tractography-Based Parcellation of Cerebellar Dentate Nuclei via a Deep Nonnegative Matrix Factorization Clustering Method

no code implementations18 Nov 2022 Xiao Xu, Yuqian Chen, Leo Zekelman, Yogesh Rathi, Nikos Makris, Fan Zhang, Lauren J. O'Donnell

In this paper, we investigate a deep nonnegative matrix factorization clustering method (DNMFC) for parcellation of the human DN based on its structural connectivity using diffusion MRI tractography.

Clustering Diffusion MRI

White Matter Tracts are Point Clouds: Neuropsychological Score Prediction and Critical Region Localization via Geometric Deep Learning

no code implementations6 Jul 2022 Yuqian Chen, Fan Zhang, Chaoyi Zhang, Tengfei Xue, Leo R. Zekelman, Jianzhong He, Yang song, Nikos Makris, Yogesh Rathi, Alexandra J. Golby, Weidong Cai, Lauren J. O'Donnell

In this paper, we propose a deep-learning-based framework for neuropsychological score prediction using microstructure measurements estimated from diffusion magnetic resonance imaging (dMRI) tractography, focusing on predicting performance on a receptive vocabulary assessment task based on a critical fiber tract for language, the arcuate fasciculus (AF).

Diffusion MRI Prediction

Deep fiber clustering: Anatomically informed fiber clustering with self-supervised deep learning for fast and effective tractography parcellation

1 code implementation2 May 2022 Yuqian Chen, Chaoyi Zhang, Tengfei Xue, Yang song, Nikos Makris, Yogesh Rathi, Weidong Cai, Fan Zhang, Lauren J. O'Donnell

In this work, we propose a novel deep learning framework for white matter fiber clustering, Deep Fiber Clustering (DFC), which solves the unsupervised clustering problem as a self-supervised learning task with a domain-specific pretext task to predict pairwise fiber distances.

Anatomy Clustering +3

SupWMA: Consistent and Efficient Tractography Parcellation of Superficial White Matter with Deep Learning

1 code implementation29 Jan 2022 Tengfei Xue, Fan Zhang, Chaoyi Zhang, Yuqian Chen, Yang song, Nikos Makris, Yogesh Rathi, Weidong Cai, Lauren J. O'Donnell

Most parcellation methods focus on the deep white matter (DWM), while fewer methods address the superficial white matter (SWM) due to its complexity.

Contrastive Learning

Deep Fiber Clustering: Anatomically Informed Unsupervised Deep Learning for Fast and Effective White Matter Parcellation

no code implementations11 Jul 2021 Yuqian Chen, Chaoyi Zhang, Yang song, Nikos Makris, Yogesh Rathi, Weidong Cai, Fan Zhang, Lauren J. O'Donnell

White matter fiber clustering (WMFC) enables parcellation of white matter tractography for applications such as disease classification and anatomical tract segmentation.

Clustering Segmentation +1

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