Organ morphology is a key indicator for prostate disease diagnosis and prognosis.
Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program.
no code implementations • 9 Jul 2018 • Yipeng Hu, Marc Modat, Eli Gibson, Wenqi Li, Nooshin Ghavami, Ester Bonmati, Guotai Wang, Steven Bandula, Caroline M. Moore, Mark Emberton, Sébastien Ourselin, J. Alison Noble, Dean C. Barratt, Tom Vercauteren
A median target registration error of 3. 6 mm on landmark centroids and a median Dice of 0. 87 on prostate glands are achieved from cross-validation experiments, in which 108 pairs of multimodal images from 76 patients were tested with high-quality anatomical labels.
During training, the registration network simultaneously aims to maximize similarity between anatomical labels that drives image alignment and to minimize an adversarial generator loss that measures divergence between the predicted- and simulated deformation.
Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms.