Search Results for author: Qingyu Chen

Found 50 papers, 26 papers with code

Automatic recognition of abdominal lymph nodes from clinical text

1 code implementation EMNLP (ClinicalNLP) 2020 Yifan Peng, SungWon Lee, Daniel C. Elton, Thomas Shen, Yu-Xing Tang, Qingyu Chen, Shuai Wang, Yingying Zhu, Ronald Summers, Zhiyong Lu

We then introduce an end-to-end approach based on the combination of rules and transformer-based methods to detect these abdominal lymph node mentions and classify their types from the MRI radiology reports.

Dialogue is Better Than Monologue: Instructing Medical LLMs via Strategical Conversations

no code implementations29 Jan 2025 Zijie Liu, Xinyu Zhao, Jie Peng, Zhuangdi Zhu, Qingyu Chen, Xia Hu, Tianlong Chen

Current medical AI systems often fail to replicate real-world clinical reasoning, as they are predominantly trained and evaluated on static text and question-answer tasks.

Enhancing Patient-Centric Communication: Leveraging LLMs to Simulate Patient Perspectives

no code implementations12 Jan 2025 Xinyao Ma, Rui Zhu, ZiHao Wang, Jingwei Xiong, Qingyu Chen, Haixu Tang, L. Jean Camp, Lucila Ohno-Machado

We evaluate and compare with human responses the comprehensibility of discharge summaries among individuals with varying educational backgrounds, using this analysis to assess the strengths and limitations of LLM-driven simulations.

Humans Continue to Outperform Large Language Models in Complex Clinical Decision-Making: A Study with Medical Calculators

no code implementations8 Nov 2024 Nicholas Wan, Qiao Jin, Joey Chan, Guangzhi Xiong, Serina Applebaum, Aidan Gilson, Reid McMurry, R. Andrew Taylor, Aidong Zhang, Qingyu Chen, Zhiyong Lu

Although large language models (LLMs) have been assessed for general medical knowledge using medical licensing exams, their ability to effectively support clinical decision-making tasks, such as selecting and using medical calculators, remains uncertain.

Decision Making Multiple-choice +1

MedINST: Meta Dataset of Biomedical Instructions

1 code implementation17 Oct 2024 Wenhan Han, Meng Fang, Zihan Zhang, Yu Yin, Zirui Song, Ling Chen, Mykola Pechenizkiy, Qingyu Chen

The integration of large language model (LLM) techniques in the field of medical analysis has brought about significant advancements, yet the scarcity of large, diverse, and well-annotated datasets remains a major challenge.

Language Modeling Language Modelling +1

LMOD: A Large Multimodal Ophthalmology Dataset and Benchmark for Large Vision-Language Models

no code implementations2 Oct 2024 Zhenyue Qin, Yu Yin, Dylan Campbell, Xuansheng Wu, Ke Zou, Yih-Chung Tham, Ninghao Liu, Xiuzhen Zhang, Qingyu Chen

The prevalence of vision-threatening eye diseases is a significant global burden, with many cases remaining undiagnosed or diagnosed too late for effective treatment.

Hallucination

Language Enhanced Model for Eye (LEME): An Open-Source Ophthalmology-Specific Large Language Model

no code implementations1 Oct 2024 Aidan Gilson, Xuguang Ai, Qianqian Xie, Sahana Srinivasan, Krithi Pushpanathan, Maxwell B. Singer, Jimin Huang, Hyunjae Kim, Erping Long, Peixing Wan, Luciano V. Del Priore, Lucila Ohno-Machado, Hua Xu, Dianbo Liu, Ron A. Adelman, Yih-Chung Tham, Qingyu Chen

In external validations, LEME excelled in long-form QA with a Rouge-L of 0. 19 (all p<0. 0001), ranked second in MCQ accuracy (0. 68; all p<0. 0001), and scored highest in EHR summarization and clinical QA (ranging from 4. 24 to 4. 83 out of 5 for correctness, completeness, and readability).

Language Modeling Language Modelling +3

Federated Graph Learning with Adaptive Importance-based Sampling

no code implementations23 Sep 2024 Anran Li, YuanYuan Chen, Chao Ren, Wenhan Wang, Ming Hu, Tianlin Li, Han Yu, Qingyu Chen

For privacy-preserving graph learning tasks involving distributed graph datasets, federated learning (FL)-based GCN (FedGCN) training is required.

Federated Learning Graph Sampling +1

Fair Text to Medical Image Diffusion Model with Subgroup Distribution Aligned Tuning

no code implementations21 Jun 2024 Xu Han, Fangfang Fan, Jingzhao Rong, Zhen Li, Georges El Fakhri, Qingyu Chen, Xiaofeng Liu

For evaluation, we set the target dataset to be enhanced as the BraST18 dataset, and trained a brain magnetic resonance (MR) slice-based gender classifier from it.

Knowledge Distillation

Augmenting Biomedical Named Entity Recognition with General-domain Resources

1 code implementation15 Jun 2024 Yu Yin, Hyunjae Kim, Xiao Xiao, Chih Hsuan Wei, Jaewoo Kang, Zhiyong Lu, Hua Xu, Meng Fang, Qingyu Chen

Specifically, our models consistently outperformed the baseline models in six out of eight entity types, achieving an average improvement of 0. 9% over the best baseline performance across eight entities.

Language Modelling Multi-Task Learning +3

Whose Side Are You On? Investigating the Political Stance of Large Language Models

1 code implementation15 Mar 2024 Pagnarasmey Pit, Xingjun Ma, Mike Conway, Qingyu Chen, James Bailey, Henry Pit, Putrasmey Keo, Watey Diep, Yu-Gang Jiang

Large Language Models (LLMs) have gained significant popularity for their application in various everyday tasks such as text generation, summarization, and information retrieval.

Fairness Information Retrieval +1

KG-Rank: Enhancing Large Language Models for Medical QA with Knowledge Graphs and Ranking Techniques

1 code implementation9 Mar 2024 Rui Yang, Haoran Liu, Edison Marrese-Taylor, Qingcheng Zeng, Yu He Ke, Wanxin Li, Lechao Cheng, Qingyu Chen, James Caverlee, Yutaka Matsuo, Irene Li

In this work, we develop an augmented LLM framework, KG-Rank, which leverages a medical knowledge graph (KG) along with ranking and re-ranking techniques, to improve the factuality of long-form question answering (QA) in the medical domain.

Knowledge Graphs Long Form Question Answering +1

Word-Sequence Entropy: Towards Uncertainty Estimation in Free-Form Medical Question Answering Applications and Beyond

no code implementations22 Feb 2024 Zhiyuan Wang, Jinhao Duan, Chenxi Yuan, Qingyu Chen, Tianlong Chen, Yue Zhang, Ren Wang, Xiaoshuang Shi, Kaidi Xu

Uncertainty estimation is crucial for the reliability of safety-critical human and artificial intelligence (AI) interaction systems, particularly in the domain of healthcare engineering.

MedQA Question Answering +1

AgentMD: Empowering Language Agents for Risk Prediction with Large-Scale Clinical Tool Learning

no code implementations20 Feb 2024 Qiao Jin, Zhizheng Wang, Yifan Yang, Qingqing Zhu, Donald Wright, Thomas Huang, W John Wilbur, Zhe He, Andrew Taylor, Qingyu Chen, Zhiyong Lu

Clinical calculators play a vital role in healthcare by offering accurate evidence-based predictions for various purposes such as prognosis.

Prognosis

Me LLaMA: Foundation Large Language Models for Medical Applications

1 code implementation20 Feb 2024 Qianqian Xie, Qingyu Chen, Aokun Chen, Cheng Peng, Yan Hu, Fongci Lin, Xueqing Peng, Jimin Huang, Jeffrey Zhang, Vipina Keloth, Xinyu Zhou, Lingfei Qian, Huan He, Dennis Shung, Lucila Ohno-Machado, Yonghui Wu, Hua Xu, Jiang Bian

This work underscores the importance of domain-specific data in developing medical LLMs and addresses the high computational costs involved in training, highlighting a balance between pre-training and fine-tuning strategies.

Few-Shot Learning

PubTator 3.0: an AI-powered Literature Resource for Unlocking Biomedical Knowledge

no code implementations19 Jan 2024 Chih-Hsuan Wei, Alexis Allot, Po-Ting Lai, Robert Leaman, Shubo Tian, Ling Luo, Qiao Jin, Zhizheng Wang, Qingyu Chen, Zhiyong Lu

PubTator 3. 0 (https://www. ncbi. nlm. nih. gov/research/pubtator3/) is a biomedical literature resource using state-of-the-art AI techniques to offer semantic and relation searches for key concepts like proteins, genetic variants, diseases, and chemicals.

Navigate Relation +1

Integrating UMLS Knowledge into Large Language Models for Medical Question Answering

1 code implementation4 Oct 2023 Rui Yang, Edison Marrese-Taylor, Yuhe Ke, Lechao Cheng, Qingyu Chen, Irene Li

Our research demonstrates the effectiveness of using UMLS-augmented LLMs and highlights the potential application value of LLMs in in medical question-answering.

Question Answering Text Generation

BioREx: Improving Biomedical Relation Extraction by Leveraging Heterogeneous Datasets

1 code implementation19 Jun 2023 Po-Ting Lai, Chih-Hsuan Wei, Ling Luo, Qingyu Chen, Zhiyong Lu

State-of-the-art methods were used primarily to train machine learning models on individual RE datasets, such as protein-protein interaction and chemical-induced disease relation.

graph construction Multi-Task Learning +2

GeneGPT: Augmenting Large Language Models with Domain Tools for Improved Access to Biomedical Information

1 code implementation19 Apr 2023 Qiao Jin, Yifan Yang, Qingyu Chen, Zhiyong Lu

In this paper, we present GeneGPT, a novel method for teaching LLMs to use the Web APIs of the National Center for Biotechnology Information (NCBI) for answering genomics questions.

In-Context Learning Retrieval

Bioformer: an efficient transformer language model for biomedical text mining

1 code implementation3 Feb 2023 Li Fang, Qingyu Chen, Chih-Hsuan Wei, Zhiyong Lu, Kai Wang

We thoroughly evaluated the performance of Bioformer as well as existing biomedical BERT models including BioBERT and PubMedBERT on 15 benchmark datasets of four different biomedical NLP tasks: named entity recognition, relation extraction, question answering and document classification.

Document Classification Language Modeling +6

AIONER: All-in-one scheme-based biomedical named entity recognition using deep learning

1 code implementation30 Nov 2022 Ling Luo, Chih-Hsuan Wei, Po-Ting Lai, Robert Leaman, Qingyu Chen, Zhiyong Lu

Biomedical named entity recognition (BioNER) seeks to automatically recognize biomedical entities in natural language text, serving as a necessary foundation for downstream text mining tasks and applications such as information extraction and question answering.

Multi-Task Learning named-entity-recognition +3

LitCovid in 2022: an information resource for the COVID-19 literature

no code implementations27 Sep 2022 Qingyu Chen, Alexis Allot, Robert Leaman, Chih-Hsuan Wei, Elaheh Aghaarabi, John J. Guerrerio, Lilly Xu, Zhiyong Lu

LitCovid (https://www. ncbi. nlm. nih. gov/research/coronavirus/), first launched in February 2020, is a first-of-its-kind literature hub for tracking up-to-date published research on COVID-19.

Comprehensively identifying Long Covid articles with human-in-the-loop machine learning

no code implementations16 Sep 2022 Robert Leaman, Rezarta Islamaj, Alexis Allot, Qingyu Chen, W. John Wilbur, Zhiyong Lu

A significant percentage of COVID-19 survivors experience ongoing multisystemic symptoms that often affect daily living, a condition known as Long Covid or post-acute-sequelae of SARS-CoV-2 infection.

Active Learning Specificity

Assigning Species Information to Corresponding Genes by a Sequence Labeling Framework

1 code implementation8 May 2022 Ling Luo, Chih-Hsuan Wei, Po-Ting Lai, Qingyu Chen, Rezarta Islamaj Doğan, Zhiyong Lu

The automatic assignment of species information to the corresponding genes in a research article is a critically important step in the gene normalization task, whereby a gene mention is normalized and linked to a database record or identifier by a text-mining algorithm.

Benchmarking Binary Classification

A Privacy-Preserving Unsupervised Domain Adaptation Framework for Clinical Text Analysis

no code implementations18 Jan 2022 Qiyuan An, Ruijiang Li, Lin Gu, Hao Zhang, Qingyu Chen, Zhiyong Lu, Fei Wang, Yingying Zhu

To evaluate our proposed method's utility and privacy loss, we apply our model on a medical report disease label classification task using two noisy challenging clinical text datasets.

Inference Attack Membership Inference Attack +4

Artificial Intelligence (AI) in Action: Addressing the COVID-19 Pandemic with Natural Language Processing (NLP)

no code implementations9 Oct 2020 Qingyu Chen, Robert Leaman, Alexis Allot, Ling Luo, Chih-Hsuan Wei, Shankai Yan, Zhiyong Lu

The COVID-19 pandemic has had a significant impact on society, both because of the serious health effects of COVID-19 and because of public health measures implemented to slow its spread.

Emotion Recognition Information Retrieval +7

Navigating the landscape of COVID-19 research through literature analysis: A bird's eye view

no code implementations7 Aug 2020 Lana Yeganova, Rezarta Islamaj, Qingyu Chen, Robert Leaman, Alexis Allot, Chin-Hsuan Wei, Donald C. Comeau, Won Kim, Yifan Peng, W. John Wilbur, Zhiyong Lu

In this study we analyze the LitCovid collection, 13, 369 COVID-19 related articles found in PubMed as of May 15th, 2020 with the purpose of examining the landscape of literature and presenting it in a format that facilitates information navigation and understanding.

Clustering named-entity-recognition +2

BioConceptVec: creating and evaluating literature-based biomedical concept embeddings on a large scale

1 code implementation23 Dec 2019 Qingyu Chen, Kyubum Lee, Shankai Yan, Sun Kim, Chih-Hsuan Wei, Zhiyong Lu

Capturing the semantics of related biological concepts, such as genes and mutations, is of significant importance to many research tasks in computational biology such as protein-protein interaction detection, gene-drug association prediction, and biomedical literature-based discovery.

Deep learning with sentence embeddings pre-trained on biomedical corpora improves the performance of finding similar sentences in electronic medical records

no code implementations6 Sep 2019 Qingyu Chen, Jingcheng Du, Sun Kim, W. John Wilbur, Zhiyong Lu

For the post challenge, the performance of both Random Forest and the Encoder Network was improved; in particular, the correlation of the Encoder Network was improved by ~13%.

Semantic Textual Similarity Sentence +2

A deep learning approach for automated detection of geographic atrophy from color fundus photographs

1 code implementation7 Jun 2019 Tiarnan D. Keenan, Shazia Dharssi, Yifan Peng, Qingyu Chen, Elvira Agrón, Wai T. Wong, Zhiyong Lu, Emily Y. Chew

Results: The deep learning models (GA detection, CGA detection from all eyes, and centrality detection from GA eyes) had AUC of 0. 933-0. 976, 0. 939-0. 976, and 0. 827-0. 888, respectively.

Deep Learning Specificity

DeepSeeNet: A deep learning model for automated classification of patient-based age-related macular degeneration severity from color fundus photographs

1 code implementation19 Nov 2018 Yifan Peng, Shazia Dharssi, Qingyu Chen, Tiarnan D. Keenan, Elvira Agrón, Wai T. Wong, Emily Y. Chew, Zhiyong Lu

DeepSeeNet simulates the human grading process by first detecting individual AMD risk factors (drusen size, pigmentary abnormalities) for each eye and then calculating a patient-based AMD severity score using the AREDS Simplified Severity Scale.

Decision Making General Classification

ML-Net: multi-label classification of biomedical texts with deep neural networks

4 code implementations13 Nov 2018 Jingcheng Du, Qingyu Chen, Yifan Peng, Yang Xiang, Cui Tao, Zhiyong Lu

Due to this nature, the multi-label text classification task is often considered to be more challenging compared to the binary or multi-class text classification problems.

Benchmarking Feature Engineering +5

BioSentVec: creating sentence embeddings for biomedical texts

4 code implementations22 Oct 2018 Qingyu Chen, Yifan Peng, Zhiyong Lu

Sentence embeddings have become an essential part of today's natural language processing (NLP) systems, especially together advanced deep learning methods.

 Ranked #1 on Sentence Embeddings For Biomedical Texts on MedSTS (using extra training data)

Benchmarking Sentence +2

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