2 code implementations • 16 Sep 2020 • Damla Senol Cali, Gurpreet S. Kalsi, Zülal Bingöl, Can Firtina, Lavanya Subramanian, Jeremie S. Kim, Rachata Ausavarungnirun, Mohammed Alser, Juan Gomez-Luna, Amirali Boroumand, Anant Nori, Allison Scibisz, Sreenivas Subramoney, Can Alkan, Saugata Ghose, Onur Mutlu
Unfortunately, it is currently bottlenecked by the computational power and memory bandwidth limitations of existing systems, as many of the steps in genome sequence analysis must process a large amount of data.
Hardware Architecture Genomics
This design choice goes directly against at least three key trends in systems that cause performance, scalability and energy bottlenecks: (1) data access from memory is already a key bottleneck as applications become more data-intensive and memory bandwidth and energy do not scale well, (2) energy consumption is a key constraint in especially mobile and server systems, (3) data movement is very expensive in terms of bandwidth, energy and latency, much more so than computation.
This requires efficient mechanisms that can provide logic in DRAM with access to CPU structures without having to communicate frequently with the CPU.