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Found 26 papers, 20 papers with code
Molecular-driven Foundation Model for Oncologic Pathology
Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks.
Multimodal Whole Slide Foundation Model for Pathology
The field of computational pathology has been transformed with recent advances in foundation models that encode histopathology region-of-interests (ROIs) into versatile and transferable feature representations via self-supervised learning (SSL).
Multistain Pretraining for Slide Representation Learning in Pathology
Existing approaches for slide representation learning extend the principles of SSL from small images (e. g., 224 x 224 patches) to entire slides, usually by aligning two different augmentations (or views) of the slide.
Multimodal Prototyping for cancer survival prediction
Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification.
HEST-1k: A Dataset for Spatial Transcriptomics and Histology Image Analysis
Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-increasing resolution and sensitivity.
Transcriptomics-guided Slide Representation Learning in Computational Pathology
Across three independent test datasets consisting of 1, 265 breast WSIs, 1, 946 lung WSIs, and 4, 584 liver WSIs, Tangle shows significantly better few-shot performance compared to supervised and SSL baselines.
Morphological Prototyping for Unsupervised Slide Representation Learning in Computational Pathology
Representation learning of pathology whole-slide images (WSIs) has been has primarily relied on weak supervision with Multiple Instance Learning (MIL).
A Foundational Multimodal Vision Language AI Assistant for Human Pathology
We compare PathChat against several multimodal vision language AI assistants as well as GPT4V, which powers the commercially available multimodal general purpose AI assistant ChatGPT-4.
A General-Purpose Self-Supervised Model for Computational Pathology
Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology.
Towards a Visual-Language Foundation Model for Computational Pathology
The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts.
Visual Language Pretrained Multiple Instance Zero-Shot Transfer for Histopathology Images
In this paper we present MI-Zero, a simple and intuitive framework for unleashing the zero-shot transfer capabilities of contrastively aligned image and text models on gigapixel histopathology whole slide images, enabling multiple downstream diagnostic tasks to be carried out by pretrained encoders without requiring any additional labels.
Incorporating intratumoral heterogeneity into weakly-supervised deep learning models via variance pooling
Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment.
Scaling Vision Transformers to Gigapixel Images via Hierarchical Self-Supervised Learning
Vision Transformers (ViTs) and their multi-scale and hierarchical variations have been successful at capturing image representations but their use has been generally studied for low-resolution images (e. g. - 256x256, 384384).
Self-Supervised Vision Transformers Learn Visual Concepts in Histopathology
Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology.
Algorithm Fairness in AI for Medicine and Healthcare
In the current development and deployment of many artificial intelligence (AI) systems in healthcare, algorithm fairness is a challenging problem in delivering equitable care.
Pan-Cancer Integrative Histology-Genomic Analysis via Interpretable Multimodal Deep Learning
To validate that these model explanations are prognostic, we further analyzed high attention morphological regions in WSIs, which indicates that tumor-infiltrating lymphocyte presence corroborates with favorable cancer prognosis on 9 out of 14 cancer types studied.
Whole Slide Images are 2D Point Clouds: Context-Aware Survival Prediction using Patch-based Graph Convolutional Networks
Cancer prognostication is a challenging task in computational pathology that requires context-aware representations of histology features to adequately infer patient survival.
Multimodal Co-Attention Transformer for Survival Prediction in Gigapixel Whole Slide Images
Survival outcome prediction is a challenging weakly-supervised and ordinal regression task in computational pathology that involves modeling complex interactions within the tumor microenvironment in gigapixel whole slide images (WSIs).
Federated Learning for Computational Pathology on Gigapixel Whole Slide Images
In this paper, we introduce privacy-preserving federated learning for gigapixel whole slide images in computational pathology using weakly-supervised attention multiple instance learning and differential privacy.
VR-Caps: A Virtual Environment for Capsule Endoscopy
Current capsule endoscopes and next-generation robotic capsules for diagnosis and treatment of gastrointestinal diseases are complex cyber-physical platforms that must orchestrate complex software and hardware functions.
Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images
CLAM is a general-purpose and adaptable method that can be used for a variety of different computational pathology tasks in both clinical and research settings.
EndoL2H: Deep Super-Resolution for Capsule Endoscopy
Although wireless capsule endoscopy is the preferred modality for diagnosis and assessment of small bowel diseases, the poor camera resolution is a substantial limitation for both subjective and automated diagnostics.
Pathomic Fusion: An Integrated Framework for Fusing Histopathology and Genomic Features for Cancer Diagnosis and Prognosis
Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data.
Weakly Supervised Prostate TMA Classification via Graph Convolutional Networks
In prostate cancer, the Gleason score is a grading system used to measure the aggressiveness of prostate cancer from the spatial organization of cells and the distribution of glands.
Semi-Supervised Histology Classification using Deep Multiple Instance Learning and Contrastive Predictive Coding
Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL).
SLAM Endoscopy enhanced by adversarial depth prediction
Medical endoscopy remains a challenging application for simultaneous localization and mapping (SLAM) due to the sparsity of image features and size constraints that prevent direct depth-sensing.
