Search Results for author: Richard M. Leahy

Found 14 papers, 4 papers with code

Neural Responses to Affective Sentences Reveal Signatures of Depression

no code implementations6 Jun 2025 Aditya Kommineni, Woojae Jeong, Kleanthis Avramidis, Colin McDaniel, Myzelle Hughes, Thomas McGee, Elsi Kaiser, Kristina Lerman, Idan A. Blank, Dani Byrd, Assal Habibi, B. Rael Cahn, Sudarsana Kadiri, Takfarinas Medani, Richard M. Leahy, Shrikanth Narayanan

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing are affected.

Diagnostic EEG +1

A Feasibility Study of Task-Based fMRI at 0.55 T

no code implementations26 May 2025 Parsa Razmara, Takfarinas Medani, Anand A. Joshi, Majid Abbasi Sisara, Ye Tian, Sophia X. Cui, Justin P. Haldar, Krishna S. Nayak, Richard M. Leahy

0. 55T MRI offers advantages compared to conventional field strengths, including reduced susceptibility artifacts and better compatibility with simultaneous EEG recordings.

Diagnostic EEG

Deep Learning Characterizes Depression and Suicidal Ideation from Eye Movements

no code implementations29 Apr 2025 Kleanthis Avramidis, Woojae Jeong, Aditya Kommineni, Sudarsana R. Kadiri, Marcus Ma, Colin McDaniel, Myzelle Hughes, Thomas McGee, Elsi Kaiser, Dani Byrd, Assal Habibi, B. Rael Cahn, Idan A. Blank, Kristina Lerman, Takfarinas Medani, Richard M. Leahy, Shrikanth Narayanan

We were able to identify depression and suicidal ideation with an area under the receiver operating curve (AUC) of 0. 793 (95% CI: 0. 765-0. 819) against healthy controls, and suicidality specifically with 0. 826 AUC (95% CI: 0. 797-0. 852).

Deep Learning Response Generation

Generalizable Representation Learning for fMRI-based Neurological Disorder Identification

1 code implementation16 Dec 2024 Wenhui Cui, Haleh Akrami, Anand A. Joshi, Richard M. Leahy

We overcome this limitation by introducing a novel representation learning strategy integrating meta-learning with self-supervised learning to improve the generalization from normal to clinical features.

Meta-Learning Representation Learning +1

Meta Transfer of Self-Supervised Knowledge: Foundation Model in Action for Post-Traumatic Epilepsy Prediction

no code implementations21 Dec 2023 Wenhui Cui, Haleh Akrami, Ganning Zhao, Anand A. Joshi, Richard M. Leahy

To explore the generalizability of the foundation model in downstream applications, we then apply the model to an unseen TBI dataset for prediction of PTE using zero-shot learning.

Epilepsy Prediction Meta-Learning +2

Neuro-GPT: Towards A Foundation Model for EEG

1 code implementation7 Nov 2023 Wenhui Cui, Woojae Jeong, Philipp Thölke, Takfarinas Medani, Karim Jerbi, Anand A. Joshi, Richard M. Leahy

To handle the scarcity and heterogeneity of electroencephalography (EEG) data for Brain-Computer Interface (BCI) tasks, and to harness the power of large publicly available data sets, we propose Neuro-GPT, a foundation model consisting of an EEG encoder and a GPT model.

EEG model +1

Toward Improved Generalization: Meta Transfer of Self-supervised Knowledge on Graphs

no code implementations16 Dec 2022 Wenhui Cui, Haleh Akrami, Anand A. Joshi, Richard M. Leahy

Transferring knowledge from a source domain with abundant training data to a target domain is effective for improving representation learning on scarce training data.

Meta-Learning Representation Learning +2

Learning from imperfect training data using a robust loss function: application to brain image segmentation

1 code implementation8 Aug 2022 Haleh Akrami, Wenhui Cui, Anand A Joshi, Richard M. Leahy

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications.

Brain Image Segmentation EEG +4

Semi-supervised Learning using Robust Loss

1 code implementation3 Mar 2022 Wenhui Cui, Haleh Akrami, Anand A. Joshi, Richard M. Leahy

The amount of manually labeled data is limited in medical applications, so semi-supervised learning and automatic labeling strategies can be an asset for training deep neural networks.

image-classification Image Classification

fMRI-Kernel Regression: A Kernel-based Method for Pointwise Statistical Analysis of rs-fMRI for Population Studies

no code implementations13 Dec 2020 Anand A. Joshi, Soyoung Choi, Haleh Akrami, Richard M. Leahy

While pointwise analysis methods are common in anatomical studies such as cortical thickness analysis and voxel- and tensor-based morphometry and its variants, such a method is lacking for rs-fMRI and could improve the utility of rs-fMRI for group studies.

Functional Connectivity Time Series Analysis

Addressing Variance Shrinkage in Variational Autoencoders using Quantile Regression

no code implementations18 Oct 2020 Haleh Akrami, Anand A. Joshi, Sergul Aydore, Richard M. Leahy

Using estimated quantiles to compute mean and variance under the Gaussian assumption, we compute reconstruction probability as a principled approach to outlier or anomaly detection.

Anomaly Detection Lesion Detection +1

Robust Variational Autoencoder for Tabular Data with Beta Divergence

no code implementations15 Jun 2020 Haleh Akrami, Sergul Aydore, Richard M. Leahy, Anand A. Joshi

The source of outliers in training data include the data collection process itself (random noise) or a malicious attacker (data poisoning) who may target to degrade the performance of the machine learning model.

Anomaly Detection Data Poisoning

Robust Variational Autoencoder

no code implementations23 May 2019 Haleh Akrami, Anand A. Joshi, Jian Li, Sergul Aydore, Richard M. Leahy

Machine learning methods often need a large amount of labeled training data.

Outlier Detection

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