Physiologically-Based Pharmacokinetic Modeling of Blood Clearance of Liver Fluorescent Markers for the Assessment of the Degree of Hepatic Ischemia-Reperfusion Injury

no code implementations • 10 Feb 2023 • Christopher Monti, Said H. Audi, Justin Womack, Seung-Keun Hong, Yongqiang Yang, Joohyun Kim, Ranjan K. Dash

Next, based on these SF concentration data, we generated a liver-centric, physiologically-based pharmacokinetic (PBPK) model of SF liver uptake and clearance via the bile.