1 code implementation • 13 Nov 2023 • Andrea Payne, Anjali Silva, Steven J. Rothstein, Paul D. McNicholas, Sanjeena Subedi
A mixture of multivariate Poisson-log normal factor analyzers is introduced by imposing constraints on the covariance matrix, which resulted in flexible models for clustering purposes.
1 code implementation • 15 Apr 2020 • Sanjeena Subedi, Ryan Browne
Due to this hierarchical structure, the MPLN model can account for over-dispersion as opposed to the traditional Poisson distribution and allows for correlation between the variables.
Computation 62H30
1 code implementation • 22 Jul 2018 • Anjali Silva, Steven J. Rothstein, Paul D. McNicholas, Sanjeena Subedi
Matrix variate distributions offer a natural way to model three-way data and mixtures of matrix variate distributions can be used to cluster three-way data.
Methodology
2 code implementations • 30 Nov 2017 • Anjali Silva, Steven J. Rothstein, Paul D. McNicholas, Sanjeena Subedi
The aim of applying mixture model-based clustering in this context is to discover groups of co-expressed genes, which can shed light on biological functions and pathways of gene products.
Methodology Quantitative Methods Computation
no code implementations • 7 Sep 2013 • Sanjeena Subedi, Paul D. McNicholas
Parameter estimation for model-based clustering using a finite mixture of normal inverse Gaussian (NIG) distributions is achieved through variational Bayes approximations.
no code implementations • 25 Jun 2013 • Ryan P. Browne, Sanjeena Subedi, Paul McNicholas
Previous work has focused on circumventing this problem by constraining the smallest eigenvalue of the component covariance matrices.
no code implementations • 23 Jun 2013 • Sanjeena Subedi, Paul D. McNicholas
Within the family setting, model selection involves choosing the member of the family, i. e., the appropriate covariance structure, in addition to the number of mixture components.