Complementary structural and functional abnormalities to localise epileptogenic tissue

no code implementations • 6 Apr 2023 • Jonathan J Horsley, Rhys H Thomas, Fahmida A Chowdhury, Beate Diehl, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Sjoerd B Vos, Matthew C Walker, Gavin P Winston, John S Duncan, Yujiang Wang, Peter N Taylor

Here, we investigate whether structural connectivity abnormalities, inferred from dMRI, may be used in conjunction with functional iEEG abnormalities to aid localisation and resection of the epileptogenic zone (EZ), and improve surgical outcomes in epilepsy.

EEG

Effects of anterior temporal lobe resection on cortical morphology

1 code implementation • 13 Dec 2022 • Karoline Leiberg, Jane de Tisi, John S Duncan, Bethany Little, Peter N Taylor, Sjoerd B Vos, Gavin P Winston, Bruno Mota, Yujiang Wang

Here, we examine the effects of this surgery on cortical morphology measured in independent variables both near the resection and remotely.

Normative brain mapping of interictal intracranial EEG to localise epileptogenic tissue

no code implementations • 10 May 2021 • Peter N Taylor, Christoforos A Papasavvas, Thomas W Owen, Gabrielle M Schroeder, Frances E Hutchings, Fahmida A Chowdhury, Beate Diehl, John S Duncan, Andrew W McEvoy, Anna Miserocchi, Jane de Tisi, Sjoerd B Vos, Matthew C Walker, Yujiang Wang

We then compared interictal recordings from 62 patients with epilepsy to the normative map to identify abnormal regions.

EEG