Search Results for author: Tiffany Y. Chen

Found 11 papers, 10 papers with code

Incorporating intratumoral heterogeneity into weakly-supervised deep learning models via variance pooling

1 code implementation17 Jun 2022 Iain Carmichael, Andrew H. Song, Richard J. Chen, Drew F. K. Williamson, Tiffany Y. Chen, Faisal Mahmood

Supervised learning tasks such as cancer survival prediction from gigapixel whole slide images (WSIs) are a critical challenge in computational pathology that requires modeling complex features of the tumor microenvironment.

Survival Prediction whole slide images

Scaling Vision Transformers to Gigapixel Images via Hierarchical Self-Supervised Learning

1 code implementation CVPR 2022 Richard J. Chen, Chengkuan Chen, Yicong Li, Tiffany Y. Chen, Andrew D. Trister, Rahul G. Krishnan, Faisal Mahmood

Vision Transformers (ViTs) and their multi-scale and hierarchical variations have been successful at capturing image representations but their use has been generally studied for low-resolution images (e. g. - 256x256, 384384).

Self-Supervised Learning Survival Prediction

Algorithm Fairness in AI for Medicine and Healthcare

no code implementations1 Oct 2021 Richard J. Chen, Tiffany Y. Chen, Jana Lipkova, Judy J. Wang, Drew F. K. Williamson, Ming Y. Lu, Sharifa Sahai, Faisal Mahmood

In the current development and deployment of many artificial intelligence (AI) systems in healthcare, algorithm fairness is a challenging problem in delivering equitable care.

Disentanglement Fairness +1

Pan-Cancer Integrative Histology-Genomic Analysis via Interpretable Multimodal Deep Learning

1 code implementation4 Aug 2021 Richard J. Chen, Ming Y. Lu, Drew F. K. Williamson, Tiffany Y. Chen, Jana Lipkova, Muhammad Shaban, Maha Shady, Mane Williams, Bumjin Joo, Zahra Noor, Faisal Mahmood

To validate that these model explanations are prognostic, we further analyzed high attention morphological regions in WSIs, which indicates that tumor-infiltrating lymphocyte presence corroborates with favorable cancer prognosis on 9 out of 14 cancer types studied.

Multimodal Deep Learning whole slide images

Fast and Scalable Image Search For Histology

1 code implementation28 Jul 2021 Chengkuan Chen, Ming Y. Lu, Drew F. K. Williamson, Tiffany Y. Chen, Andrew J. Schaumberg, Faisal Mahmood

Similar pathology image search offers the opportunity to comb through large historical repositories of gigapixel WSIs to identify cases with similar morphological features and can be particularly useful for diagnosing rare diseases, identifying similar cases for predicting prognosis, treatment outcomes, and potential clinical trial success.

Image Retrieval Retrieval +1

Whole Slide Images are 2D Point Clouds: Context-Aware Survival Prediction using Patch-based Graph Convolutional Networks

1 code implementation27 Jul 2021 Richard J. Chen, Ming Y. Lu, Muhammad Shaban, Chengkuan Chen, Tiffany Y. Chen, Drew F. K. Williamson, Faisal Mahmood

Cancer prognostication is a challenging task in computational pathology that requires context-aware representations of histology features to adequately infer patient survival.

Survival Prediction whole slide images

Deep Learning-based Frozen Section to FFPE Translation

1 code implementation25 Jul 2021 Kutsev Bengisu Ozyoruk, Sermet Can, Guliz Irem Gokceler, Kayhan Basak, Derya Demir, Gurdeniz Serin, Uguray Payam Hacisalihoglu, Emirhan Kurtuluş, Berkan Darbaz, Ming Y. Lu, Tiffany Y. Chen, Drew F. K. Williamson, Funda Yilmaz, Faisal Mahmood, Mehmet Turan

In this paper, we propose an artificial intelligence (AI) method that improves FS image quality by computationally transforming frozen-sectioned whole-slide images (FS-WSIs) into whole-slide FFPE-style images in minutes.

Decision Making Translation +1

Multimodal Co-Attention Transformer for Survival Prediction in Gigapixel Whole Slide Images

1 code implementation ICCV 2021 Richard J. Chen, Ming Y. Lu, Wei-Hung Weng, Tiffany Y. Chen, Drew F.K. Williamson, Trevor Manz, Maha Shady, Faisal Mahmood

Survival outcome prediction is a challenging weakly-supervised and ordinal regression task in computational pathology that involves modeling complex interactions within the tumor microenvironment in gigapixel whole slide images (WSIs).

Multiple Instance Learning Question Answering +5

Federated Learning for Computational Pathology on Gigapixel Whole Slide Images

1 code implementation21 Sep 2020 Ming Y. Lu, Dehan Kong, Jana Lipkova, Richard J. Chen, Rajendra Singh, Drew F. K. Williamson, Tiffany Y. Chen, Faisal Mahmood

In this paper, we introduce privacy-preserving federated learning for gigapixel whole slide images in computational pathology using weakly-supervised attention multiple instance learning and differential privacy.

Federated Learning Multiple Instance Learning +3

Deep Learning-based Computational Pathology Predicts Origins for Cancers of Unknown Primary

1 code implementation24 Jun 2020 Ming Y. Lu, Melissa Zhao, Maha Shady, Jana Lipkova, Tiffany Y. Chen, Drew F. K. Williamson, Faisal Mahmood

Cancer of unknown primary (CUP) is an enigmatic group of diagnoses where the primary anatomical site of tumor origin cannot be determined.

whole slide images

Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images

1 code implementation20 Apr 2020 Ming Y. Lu, Drew F. K. Williamson, Tiffany Y. Chen, Richard J. Chen, Matteo Barbieri, Faisal Mahmood

CLAM is a general-purpose and adaptable method that can be used for a variety of different computational pathology tasks in both clinical and research settings.

Domain Adaptation Multiple Instance Learning +2

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