no code implementations • 12 Mar 2023 • Qian Li, Yunguan Fu, Qianye Yang, Zhijiang Du, Hongjian Yu, Yipeng Hu
Graph neural networks (GNNs) have been proposed for medical image segmentation, by predicting anatomical structures represented by graphs of vertices and edges.
1 code implementation • 10 Mar 2023 • Yunguan Fu, Yiwen Li, Shaheer U. Saeed, Matthew J. Clarkson, Yipeng Hu
Recently, denoising diffusion probabilistic models (DDPM) have been applied to image segmentation by generating segmentation masks conditioned on images, while the applications were mainly limited to 2D networks without exploiting potential benefits from the 3D formulation.
no code implementations • 3 Mar 2023 • Shaheer U. Saeed, Tom Syer, Wen Yan, Qianye Yang, Mark Emberton, Shonit Punwani, Matthew J. Clarkson, Dean C. Barratt, Yipeng Hu
For the first time, we evaluate the realism of the generated pathology by blind expert identification of the presence of suspected lesions, where we find that the clinician performs similarly for both real and synthesised images, with a 2. 9 percentage point difference in lesion identification accuracy between real and synthesised images, demonstrating the potentials in radiological training purposes.
no code implementations • 20 Feb 2023 • Zhe Min, Zachary M. C. Baum, Shaheer U. Saeed, Mark Emberton, Dean C. Barratt, Zeike A. Taylor, Yipeng Hu
Biomechanical modelling of soft tissue provides a non-data-driven method for constraining medical image registration, such that the estimated spatial transformation is considered biophysically plausible.
no code implementations • 3 Dec 2022 • Shaheer U. Saeed, João Ramalhinho, Mark Pinnock, Ziyi Shen, Yunguan Fu, Nina Montaña-Brown, Ester Bonmati, Dean C. Barratt, Stephen P. Pereira, Brian Davidson, Matthew J. Clarkson, Yipeng Hu
In this work, the task predictor is a segmentation network.
1 code implementation • 9 Nov 2022 • Qi Li, Ziyi Shen, Qian Li, Dean C Barratt, Thomas Dowrick, Matthew J Clarkson, Tom Vercauteren, Yipeng Hu
Little benefit was observed by adding frames more than one second away from the predicted transformation, with or without LSTM-based RNNs.
1 code implementation • 4 Nov 2022 • M. Jorge Cardoso, Wenqi Li, Richard Brown, Nic Ma, Eric Kerfoot, Yiheng Wang, Benjamin Murrey, Can Zhao, Dong Yang, Vishwesh Nath, Yufan He, Ziyue Xu, Ali Hatamizadeh, Andriy Myronenko, Wentao Zhu, Yun Liu, Mingxin Zheng, Yucheng Tang, Isaac Yang, Michael Zephyr, Behrooz Hashemian, Sachidanand Alle, Mohammad Zalbagi Darestani, Charlie Budd, Marc Modat, Tom Vercauteren, Guotai Wang, Yiwen Li, Yipeng Hu, Yunguan Fu, Benjamin Gorman, Hans Johnson, Brad Genereaux, Barbaros S. Erdal, Vikash Gupta, Andres Diaz-Pinto, Andre Dourson, Lena Maier-Hein, Paul F. Jaeger, Michael Baumgartner, Jayashree Kalpathy-Cramer, Mona Flores, Justin Kirby, Lee A. D. Cooper, Holger R. Roth, Daguang Xu, David Bericat, Ralf Floca, S. Kevin Zhou, Haris Shuaib, Keyvan Farahani, Klaus H. Maier-Hein, Stephen Aylward, Prerna Dogra, Sebastien Ourselin, Andrew Feng
For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e. g. geometry, physiology, physics) of medical data being processed.
no code implementations • 27 Oct 2022 • Zachary M. C. Baum, Yipeng Hu, Dean Barratt
We present a meta-learning framework for interactive medical image registration.
1 code implementation • 12 Sep 2022 • Yiwen Li, Yunguan Fu, Iani Gayo, Qianye Yang, Zhe Min, Shaheer Saeed, Wen Yan, Yipei Wang, J. Alison Noble, Mark Emberton, Matthew J. Clarkson, Henkjan Huisman, Dean Barratt, Victor Adrian Prisacariu, Yipeng Hu
The prowess that makes few-shot learning desirable in medical image analysis is the efficient use of the support image data, which are labelled to classify or segment new classes, a task that otherwise requires substantially more training images and expert annotations.
no code implementations • 5 Sep 2022 • Sulaiman Vesal, Iani Gayo, Indrani Bhattacharya, Shyam Natarajan, Leonard S. Marks, Dean C Barratt, Richard E. Fan, Yipeng Hu, Geoffrey A. Sonn, Mirabela Rusu
We trained our model on 764 subjects from one institution and finetuned our model using only ten subjects from subsequent institutions.
no code implementations • 22 Aug 2022 • Shahab Aslani, Watjana Lilaonitkul, Vaishnavi Gnanananthan, Divya Raj, Bojidar Rangelov, Alexandra L Young, Yipeng Hu, Paul Taylor, Daniel C Alexander, Joseph Jacob
This variation is seen in the CXR projections used, image annotations added and in the inspiratory effort and degree of rotation of clinical images.
1 code implementation • 8 Aug 2022 • Mou-Cheng Xu, Yukun Zhou, Chen Jin, Marius de Groot, Daniel C. Alexander, Neil P. Oxtoby, Yipeng Hu, Joseph Jacob
Secondly, we propose a semi-supervised medical image segmentation method purely based on the original pseudo labelling, namely SegPL.
1 code implementation • 26 Jul 2022 • Qianye Yang, David Atkinson, Yunguan Fu, Tom Syer, Wen Yan, Shonit Punwani, Matthew J. Clarkson, Dean C. Barratt, Tom Vercauteren, Yipeng Hu
In this work, we consider the task of pairwise cross-modality image registration, which may benefit from exploiting additional images available only at training time from an additional modality that is different to those being registered.
no code implementations • 22 Jul 2022 • Zachary MC Baum, Tamas Ungi, Christopher Schlenger, Yipeng Hu, Dean C Barratt
This makes FPT amenable to real-world medical imaging applications where ground-truth deformations may be infeasible to obtain, or in scenarios where only a varying degree of completeness in the point sets to be aligned is available.
no code implementations • 22 Jul 2022 • Zachary MC Baum, Yipeng Hu, Dean C Barratt
Such networks can be trained by aligning the training image pairs while simultaneously improving test-time optimization efficacy; tasks which were previously considered two independent training and optimization processes.
no code implementations • 22 Jul 2022 • Pierre Raillard, Lorenzo Cristoni, Andrew Walden, Roberto Lazzari, Thomas Pulimood, Louis Grandjean, Claudia AM Gandini Wheeler-Kingshott, Yipeng Hu, Zachary MC Baum
This work focuses on leveraging 'off-the-shelf' pre-trained models as deep feature extractors for scoring disease severity with minimal training time.
no code implementations • 21 Jul 2022 • Iani JMB Gayo, Shaheer U. Saeed, Dean C. Barratt, Matthew J. Clarkson, Yipeng Hu
However, the diagnostic accuracy of the biopsy procedure is limited by the operator-dependent skills and experience in sampling the targets, a sequential decision making process that involves navigating an ultrasound probe and placing a series of sampling needles for potentially multiple targets.
no code implementations • 13 Jul 2022 • Ziyi Shen, Qianye Yang, Yuming Shen, Francesco Giganti, Vasilis Stavrinides, Richard Fan, Caroline Moore, Mirabela Rusu, Geoffrey Sonn, Philip Torr, Dean Barratt, Yipeng Hu
Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients.
no code implementations • 30 Mar 2022 • Wen Yan, Qianye Yang, Tom Syer, Zhe Min, Shonit Punwani, Mark Emberton, Dean C. Barratt, Bernard Chiu, Yipeng Hu
However, the differences in false-positives and false-negatives, between the actual errors and the perceived counterparts if DSC is used, can be as high as 152 and 154, respectively, out of the 357 test set lesions.
1 code implementation • 27 Mar 2022 • Shaheer U. Saeed, Yunguan Fu, Vasilis Stavrinides, Zachary M. C. Baum, Qianye Yang, Mirabela Rusu, Richard E. Fan, Geoffrey A. Sonn, J. Alison Noble, Dean C. Barratt, Yipeng Hu
In this paper, we consider image quality assessment (IQA) as a measure of how images are amenable with respect to a given downstream task, or task amenability.
no code implementations • 12 Mar 2022 • Yukun Zhou, MouCheng Xu, Yipeng Hu, Stefano B. Blumberg, An Zhao, Siegfried K. Wagner, Pearse A. Keane, Daniel C. Alexander
Estimating clinically-relevant vascular features following vessel segmentation is a standard pipeline for retinal vessel analysis, which provides potential ocular biomarkers for both ophthalmic disease and systemic disease.
1 code implementation • 20 Feb 2022 • Shaheer U. Saeed, Wen Yan, Yunguan Fu, Francesco Giganti, Qianye Yang, Zachary M. C. Baum, Mirabela Rusu, Richard E. Fan, Geoffrey A. Sonn, Mark Emberton, Dean C. Barratt, Yipeng Hu
This allows for the trained IQA controller to measure the impact an image has on the target task performance, when this task is performed using the predictor, e. g. segmentation and classification neural networks in modern clinical applications.
no code implementations • 17 Jan 2022 • Yiwen Li, Yunguan Fu, Qianye Yang, Zhe Min, Wen Yan, Henkjan Huisman, Dean Barratt, Victor Adrian Prisacariu, Yipeng Hu
The ability to adapt medical image segmentation networks for a novel class such as an unseen anatomical or pathological structure, when only a few labelled examples of this class are available from local healthcare providers, is sought-after.
1 code implementation • 19 Nov 2021 • Ashkan Pakzad, Wing Keung Cheung, Kin Quan, Nesrin Mogulkoc, Coline H. M. Van Moorsel, Brian J. Bartholmai, Hendrik W. Van Es, Alper Ezircan, Frouke Van Beek, Marcel Veltkamp, Ronald Karwoski, Tobias Peikert, Ryan D. Clay, Finbar Foley, Cassandra Braun, Recep Savas, Carole Sudre, Tom Doel, Daniel C. Alexander, Peter Wijeratne, David Hawkes, Yipeng Hu, John R Hurst, Joseph Jacob
AirQuant is an open-source pipeline that avoids limitations of existing airway quantification algorithms and has clinical interpretability.
1 code implementation • 22 Oct 2021 • Yiwen Li, Gratianus Wesley Putra Data, Yunguan Fu, Yipeng Hu, Victor Adrian Prisacariu
Despite the success of deep learning methods for semantic segmentation, few-shot semantic segmentation remains a challenging task due to the limited training data and the generalisation requirement for unseen classes.
no code implementations • 12 Oct 2021 • Ester Bonmati, Yipeng Hu, Alexander Grimwood, Gavin J. Johnson, George Goodchild, Margaret G. Keane, Kurinchi Gurusamy, Brian Davidson, Matthew J. Clarkson, Stephen P. Pereira, Dean C. Barratt
In this work, we propose a multi-modal convolutional neural network (CNN) architecture that labels endoscopic ultrasound (EUS) images from raw verbal comments provided by a clinician during the procedure.
no code implementations • 10 Sep 2021 • Zachary M C Baum, Yipeng Hu, Dean C Barratt
Consisting of two modules, a global feature extraction module and a point transformation module, FPT does not assume explicit constraints based on point vicinity, thereby overcoming a common requirement of previous learning-based point-set registration methods.
no code implementations • 6 Aug 2021 • Harry Mason, Lorenzo Cristoni, Andrew Walden, Roberto Lazzari, Thomas Pulimood, Louis Grandjean, Claudia AM Gandini Wheeler-Kingshott, Yipeng Hu, Zachary MC Baum
Furthermore, we offer a possible explanation that correlates the segmentation performance to label consistency and data domain diversity in this point-of-care lung ultrasound application.
1 code implementation • 31 Jul 2021 • Shaheer U. Saeed, Yunguan Fu, Vasilis Stavrinides, Zachary M. C. Baum, Qianye Yang, Mirabela Rusu, Richard E. Fan, Geoffrey A. Sonn, J. Alison Noble, Dean C. Barratt, Yipeng Hu
Using 6644 clinical ultrasound images from 249 prostate cancer patients, our results for image classification and segmentation tasks show that the proposed IQA method can be adapted using data with as few as respective 19. 7% and 29. 6% expert-reviewed consensus labels and still achieve comparable IQA and task performance, which would otherwise require a training dataset with 100% expert labels.
1 code implementation • 28 Jul 2021 • Liam F Chalcroft, Jiongqi Qu, Sophie A Martin, Iani JMB Gayo, Giulio V Minore, Imraj RD Singh, Shaheer U Saeed, Qianye Yang, Zachary MC Baum, Andre Altmann, Yipeng Hu
When developing deep neural networks for segmenting intraoperative ultrasound images, several practical issues are encountered frequently, such as the presence of ultrasound frames that do not contain regions of interest and the high variance in ground-truth labels.
no code implementations • 4 Jun 2021 • Zhe Min, Fernando J. Bianco, Qianye Yang, Rachael Rodell, Wen Yan, Dean Barratt, Yipeng Hu
Prostate cancer (PCa) is one of the leading causes of death for men worldwide.
2 code implementations • 25 Apr 2021 • Yukun Zhou, MouCheng Xu, Yipeng Hu, Hongxiang Lin, Joseph Jacob, Pearse A. Keane, Daniel C. Alexander
Accurate multi-class segmentation is a long-standing challenge in medical imaging, especially in scenarios where classes share strong similarity.
no code implementations • 15 Feb 2021 • Shaheer U. Saeed, Yunguan Fu, Zachary M. C. Baum, Qianye Yang, Mirabela Rusu, Richard E. Fan, Geoffrey A. Sonn, Dean C. Barratt, Yipeng Hu
In this paper, we consider a type of image quality assessment as a task-specific measurement, which can be used to select images that are more amenable to a given target task, such as image classification or segmentation.
no code implementations • 16 Jan 2021 • Qianye Yang, Tom Vercauteren, Yunguan Fu, Francesco Giganti, Nooshin Ghavami, Vasilis Stavrinides, Caroline Moore, Matt Clarkson, Dean Barratt, Yipeng Hu
Organ morphology is a key indicator for prostate disease diagnosis and prognosis.
1 code implementation • 4 Nov 2020 • Yunguan Fu, Nina Montaña Brown, Shaheer U. Saeed, Adrià Casamitjana, Zachary M. C. Baum, Rémi Delaunay, Qianye Yang, Alexander Grimwood, Zhe Min, Stefano B. Blumberg, Juan Eugenio Iglesias, Dean C. Barratt, Ester Bonmati, Daniel C. Alexander, Matthew J. Clarkson, Tom Vercauteren, Yipeng Hu
DeepReg (https://github. com/DeepRegNet/DeepReg) is a community-supported open-source toolkit for research and education in medical image registration using deep learning.
no code implementations • 6 Oct 2020 • Alexander Grimwood, Helen McNair, Yipeng Hu, Ester Bonmati, Dean Barratt, Emma Harris
For images with unanimous consensus between observers, anatomical classification accuracy was 97. 2% and probe adjustment accuracy was 94. 9%.
no code implementations • 29 Aug 2020 • Qianye Yang, Yunguan Fu, Francesco Giganti, Nooshin Ghavami, Qingchao Chen, J. Alison Noble, Tom Vercauteren, Dean Barratt, Yipeng Hu
Morphological analysis of longitudinal MR images plays a key role in monitoring disease progression for prostate cancer patients, who are placed under an active surveillance program.
no code implementations • 20 Aug 2020 • Zachary M. C. Baum, Ester Bonmati, Lorenzo Cristoni, Andrew Walden, Ferran Prados, Baris Kanber, Dean C. Barratt, David J. Hawkes, Geoffrey J M Parker, Claudia A M Gandini Wheeler-Kingshott, Yipeng Hu
The diagnosis assistance module can then be trained with data that are deemed of sufficient quality, guaranteed by the closed-loop feedback mechanism from the quality assessment module.
no code implementations • 5 Aug 2020 • Zachary M. C. Baum, Yipeng Hu, Dean C. Barratt
We describe a point-set registration algorithm based on a novel free point transformer (FPT) network, designed for points extracted from multimodal biomedical images for registration tasks, such as those frequently encountered in ultrasound-guided interventional procedures.
no code implementations • 9 Jul 2020 • Shaheer U. Saeed, Zeike A. Taylor, Mark A. Pinnock, Mark Emberton, Dean C. Barratt, Yipeng Hu
Based on 160, 000 nonlinear FE simulations on clinical imaging data from 320 patients, we demonstrate that the trained networks generalise to unstructured point sets sampled directly from holdout patient segmentation, yielding a near real-time inference and an expected error of 0. 017 mm in predicted nodal displacement.
no code implementations • 19 May 2020 • Yipeng Hu, Joseph Jacob, Geoffrey JM Parker, David J. Hawkes, John R. Hurst, Danail Stoyanov
The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2, emerged into a world being rapidly transformed by artificial intelligence (AI) based on big data, computational power and neural networks.
no code implementations • 20 Aug 2019 • Yunguan Fu, Maria R. Robu, Bongjin Koo, Crispin Schneider, Stijn van Laarhoven, Danail Stoyanov, Brian Davidson, Matthew J. Clarkson, Yipeng Hu
Improving a semi-supervised image segmentation task has the option of adding more unlabelled images, labelling the unlabelled images or combining both, as neither image acquisition nor expert labelling can be considered trivial in most clinical applications.
no code implementations • 30 Jun 2019 • Yipeng Hu, Eli Gibson, Dean C. Barratt, Mark Emberton, J. Alison Noble, Tom Vercauteren
Classical pairwise image registration methods search for a spatial transformation that optimises a numerical measure that indicates how well a pair of moving and fixed images are aligned.
no code implementations • 9 Jul 2018 • Yipeng Hu, Marc Modat, Eli Gibson, Wenqi Li, Nooshin Ghavami, Ester Bonmati, Guotai Wang, Steven Bandula, Caroline M. Moore, Mark Emberton, Sébastien Ourselin, J. Alison Noble, Dean C. Barratt, Tom Vercauteren
A median target registration error of 3. 6 mm on landmark centroids and a median Dice of 0. 87 on prostate glands are achieved from cross-validation experiments, in which 108 pairs of multimodal images from 76 patients were tested with high-quality anatomical labels.
1 code implementation • 27 May 2018 • Yipeng Hu, Eli Gibson, Nooshin Ghavami, Ester Bonmati, Caroline M. Moore, Mark Emberton, Tom Vercauteren, J. Alison Noble, Dean C. Barratt
During training, the registration network simultaneously aims to maximize similarity between anatomical labels that drives image alignment and to minimize an adversarial generator loss that measures divergence between the predicted- and simulated deformation.
no code implementations • 18 Dec 2017 • Ester Bonmati, Yipeng Hu, Nikhil Sindhwani, Hans Peter Dietz, Jan D'hooge, Dean Barratt, Jan Deprest, Tom Vercauteren
Results show a median Dice similarity coefficient of 0. 90 with an interquartile range of 0. 08, with equivalent performance to the three operators (with a Williams' index of 1. 03), and outperforming a U-Net architecture without the need for batch normalisation.
1 code implementation • 5 Nov 2017 • Yipeng Hu, Marc Modat, Eli Gibson, Nooshin Ghavami, Ester Bonmati, Caroline M. Moore, Mark Emberton, J. Alison Noble, Dean C. Barratt, Tom Vercauteren
Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms.
10 code implementations • 11 Sep 2017 • Eli Gibson, Wenqi Li, Carole Sudre, Lucas Fidon, Dzhoshkun I. Shakir, Guotai Wang, Zach Eaton-Rosen, Robert Gray, Tom Doel, Yipeng Hu, Tom Whyntie, Parashkev Nachev, Marc Modat, Dean C. Barratt, Sébastien Ourselin, M. Jorge Cardoso, Tom Vercauteren
NiftyNet provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications.
no code implementations • 5 Sep 2017 • Yipeng Hu, Eli Gibson, Tom Vercauteren, Hashim U. Ahmed, Mark Emberton, Caroline M. Moore, J. Alison Noble, Dean C. Barratt
In this paper, we describe how a patient-specific, ultrasound-probe-induced prostate motion model can be directly generated from a single preoperative MR image.
no code implementations • 17 Jul 2017 • Yipeng Hu, Eli Gibson, Li-Lin Lee, Weidi Xie, Dean C. Barratt, Tom Vercauteren, J. Alison Noble
Sonography synthesis has a wide range of applications, including medical procedure simulation, clinical training and multimodality image registration.