no code implementations • 4 May 2024 • Srijit Seal, Maria-Anna Trapotsi, Ola Spjuth, Shantanu Singh, Jordi Carreras-Puigvert, Nigel Greene, Andreas Bender, Anne E. Carpenter
High-content image-based assays have fueled significant discoveries in the life sciences in the past decade (2013-2023), including novel insights into disease etiology, mechanism of action, new therapeutics, and toxicology predictions.
no code implementations • 3 Feb 2024 • Erin Weisbart, Ankur Kumar, John Arevalo, Anne E. Carpenter, Beth A. Cimini, Shantanu Singh
Image-based or morphological profiling is a rapidly expanding field wherein cells are "profiled" by extracting hundreds to thousands of unbiased, quantitative features from images of cells that have been perturbed by genetic or chemical perturbations.
1 code implementation • 22 Nov 2023 • Erik Serrano, Srinivas Niranj Chandrasekaran, Dave Bunten, Kenneth I. Brewer, Jenna Tomkinson, Roshan Kern, Michael Bornholdt, Stephen Fleming, Ruifan Pei, John Arevalo, Hillary Tsang, Vincent Rubinetti, Callum Tromans-Coia, Tim Becker, Erin Weisbart, Charlotte Bunne, Alexandr A. Kalinin, Rebecca Senft, Stephen J. Taylor, Nasim Jamali, Adeniyi Adeboye, Hamdah Shafqat Abbasi, Allen Goodman, Juan C. Caicedo, Anne E. Carpenter, Beth A. Cimini, Shantanu Singh, Gregory P. Way
Technological advances in high-throughput microscopy have facilitated the acquisition of cell images at a rapid pace, and data pipelines can now extract and process thousands of image-based features from microscopy images.
no code implementations • 28 Jun 2023 • Marzieh Haghighi, Mario C. Cruz, Erin Weisbart, Beth A. Cimini, Avtar Singh, Julia Bauman, Maria E. Lozada, Sanam L. Kavari, James T. Neal, Paul C. Blainey, Anne E. Carpenter, Shantanu Singh
Various strategies for label-scarce object detection have been explored by the computer vision research community.
no code implementations • 4 Aug 2021 • David R. Stirling, Anne E. Carpenter, Beth A. Cimini
Image-based experiments can yield many thousands of individual measurements describing each object of interest, such as cells in microscopy screens.
no code implementations • CVPR 2018 • Juan C. Caicedo, Claire McQuin, Allen Goodman, Shantanu Singh, Anne E. Carpenter
Many new applications in drug discovery and functional genomics require capturing the morphology of individual imaged cells as comprehensively as possible rather than measuring one particular feature.
2 code implementations • 25 Apr 2018 • Jane Hung, Deepali Ravel, Stefanie C. P. Lopes, Gabriel Rangel, Odailton Amaral Nery, Benoit Malleret, Francois Nosten, Marcus V. G. Lacerda, Marcelo U. Ferreira, Laurent Rénia, Manoj T. Duraisingh, Fabio T. M. Costa, Matthias Marti, Anne E. Carpenter
Deep learning based models have had great success in object detection, but the state of the art models have not yet been widely applied to biological image data.