Search Results for author: James Holehouse

Found 5 papers, 1 papers with code

Principles of bursty mRNA expression and irreversibility in single cells and extrinsically varying populations

no code implementations21 May 2024 James Holehouse

The canonical model of mRNA expression is the telegraph model, describing a gene that switches on and off, subject to transcription and decay.

Non-equilibrium time-dependent solution to discrete choice with social interactions

1 code implementation20 Sep 2021 James Holehouse, Hector Pollitt

Finally, we use our time-dependent solution to construct a likelihood function that can be used on non-equilibrium data for model calibration.

Steady-state fluctuations of a genetic feedback loop with fluctuating rate parameters using the unified colored noise approximation

no code implementations4 Apr 2020 James Holehouse, Abhishek Gupta, Ramon Grima

A common model of stochastic auto-regulatory gene expression describes promoter switching via cooperative protein binding, effective protein production in the active state and dilution of proteins.

Translation

Cross-situational learning of large lexicons with finite memory

no code implementations28 Sep 2018 James Holehouse, Richard A. Blythe

Cross-situational word learning, wherein a learner combines information about possible meanings of a word across multiple exposures, has previously been shown to be a very powerful strategy to acquire a large lexicon in a short time.

Two-sample testing

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