Building population models for large-scale neural recordings: opportunities and pitfalls

3 Feb 2021  ·  Cole Hurwitz, Nina Kudryashova, Arno Onken, Matthias H. Hennig ·

Modern recording technologies now enable simultaneous recording from large numbers of neurons. This has driven the development of new statistical models for analyzing and interpreting neural population activity. Here we provide a broad overview of recent developments in this area. We compare and contrast different approaches, highlight strengths and limitations, and discuss biological and mechanistic insights that these methods provide.

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