Robust, fast and accurate: a 3-step method for automatic histological image registration

28 Mar 2019Johannes LotzNick WeissStefan Heldmann

We present a 3-step registration pipeline for differently stained histological serial sections that consists of 1) a robust pre-alignment, 2) a parametric registration computed on coarse resolution images, and 3) an accurate nonlinear registration. In all three steps the NGF distance measure is minimized with respect to an increasingly flexible transformation... (read more)

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