VESICLE: Volumetric Evaluation of Synaptic Interfaces using Computer vision at Large Scale

14 Mar 2014William Gray RoncalMichael PekalaVerena Kaynig-FittkauDean M. KleissasJoshua T. VogelsteinHanspeter PfisterRandal BurnsR. Jacob VogelsteinMark A. ChevilletGregory D. Hager

An open challenge problem at the forefront of modern neuroscience is to obtain a comprehensive mapping of the neural pathways that underlie human brain function; an enhanced understanding of the wiring diagram of the brain promises to lead to new breakthroughs in diagnosing and treating neurological disorders. Inferring brain structure from image data, such as that obtained via electron microscopy (EM), entails solving the problem of identifying biological structures in large data volumes... (read more)

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