Trajectory inference for a branching SDE model of cell differentiation

1 code implementation • 15 Jul 2023 • Elias Ventre, Aden Forrow, Nitya Gadhiwala, Parijat Chakraborty, Omer Angel, Geoffrey Schiebinger

Building on Global Waddington-OT (gWOT), which performs trajectory inference with rigorous theoretical guarantees when birth and death can be neglected, we show how to use lineage trees available with recently developed CRISPR-based measurement technologies to disentangle proliferation and differentiation.

Statistical Optimal Transport via Factored Couplings

no code implementations • 19 Jun 2018 • Aden Forrow, Jan-Christian Hütter, Mor Nitzan, Philippe Rigollet, Geoffrey Schiebinger, Jonathan Weed

We propose a new method to estimate Wasserstein distances and optimal transport plans between two probability distributions from samples in high dimension.

Domain Adaptation