Learning to automate cryo-electron microscopy data collection with Ptolemy

1 code implementation • 1 Dec 2021 • Paul T. Kim, Alex J. Noble, Anchi Cheng, Tristan Bepler

Automating this is non-trivial: the images suffer from low signal-to-noise ratio and are affected by a range of experimental parameters that can differ for each collection session.

Cryogenic Electron Microscopy (cryo-EM) Navigate

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

1 code implementation • 22 Mar 2018 • Tristan Bepler, Andrew Morin, Julia Brasch, Lawrence Shapiro, Alex J. Noble, Bonnie Berger

Cryo-electron microscopy (cryoEM) is an increasingly popular method for protein structure determination.