no code implementations • 18 Oct 2021 • A. R. Batista-Tomas, Andrea De Martino, Roberto Mulet
We solve MacArthur's resource-competition model with random species-resource couplings in the `thermodynamic' limit of infinitely many species and resources using dynamical path-integrals a la De Domincis.
1 code implementation • 6 Apr 2021 • Anna Paola Muntoni, Alfredo Braunstein, Andrea Pagnani, Daniele De Martino, Andrea De Martino
The constrained optimization of evolutionarily-motivated objective functions like the growth rate has emerged as the key theoretical assumption for the study of bacterial metabolism.
no code implementations • 30 Oct 2017 • Chiara Enrico Bena, Marco Del Giudice, Alice Grob, Thomas Gueudré, Mattia Miotto, Dimitra Gialama, Matteo Osella, Emilia Turco, Francesca Ceroni, Andrea De Martino, Carla Bosia
Our results (i) uncover and quantify a previously unnoticed heterogeneity in the growth dynamics of cancer cell populations; (ii) unveil how population growth may be affected by single-cell adaptation times; (iii) contribute to our understanding of the clinically-observed dependence of the primary and metastatic tumor take rates on the initial density of implanted cancer cells.
