no code implementations • 10 Feb 2020 • Elsi Ferro, Chiara Enrico Bena, Silvia Grigolon, Carla Bosia
In this Mini Review, we focus on the miRNA role in noise processing and on the inference of the parameters defined by the related theoretical modelling.
no code implementations • 30 Oct 2017 • Chiara Enrico Bena, Marco Del Giudice, Alice Grob, Thomas Gueudré, Mattia Miotto, Dimitra Gialama, Matteo Osella, Emilia Turco, Francesca Ceroni, Andrea De Martino, Carla Bosia
Our results (i) uncover and quantify a previously unnoticed heterogeneity in the growth dynamics of cancer cell populations; (ii) unveil how population growth may be affected by single-cell adaptation times; (iii) contribute to our understanding of the clinically-observed dependence of the primary and metastatic tumor take rates on the initial density of implanted cancer cells.