no code implementations • 23 Sep 2023 • Jamie Porthiyas, Daniel Nussey, Catherine A. A. Beauchemin, Donald C. Warren, Christian Quirouette, Kathleen P. Wilkie
Mathematical models (MMs) are a powerful tool to help us understand and predict the dynamics of tumour growth under various conditions.
1 code implementation • 1 Aug 2022 • Christian Quirouette, Daniel Cresta, Jizhou Li, Kathleen P. Wilkie, Haozhao Liang, Catherine A. A. Beauchemin
We show that infections wherein virus is release by an infected cell as a single burst, rather than at a constant rate over the cell's infectious lifespan, has the same probability of infection extinction, despite previous claims to this effect [Pearson 2011, doi:10. 1371/journal. pcbi. 1001058].
no code implementations • 10 Feb 2021 • Kenneth Blahut, Christian Quirouette, Jordan J. Feld, Shingo Iwami, Catherine A. A. Beauchemin
Experiments have shown that hepatitis C virus (HCV) infections in vitro disseminate both distally via the release and diffusion of cell-free virus through the medium, and locally via direct, cell-to-cell transmission.
no code implementations • 19 Oct 2020 • Laura E. Liao, Jonathan Carruthers, Sophie J. Smither, CL4 Virology Team, Simon A. Weller, Diane Williamson, Thomas R. Laws, Isabel Garcia-Dorival, Julian Hiscox, Benjamin P. Holder, Catherine A. A. Beauchemin, Alan S. Perelson, Martin Lopez-Garcia, Grant Lythe, John Barr, Carmen Molina-Paris
Mathematical modelling has successfully been used to provide quantitative descriptions of many viral infections, but for the Ebola virus, which requires biosafety level 4 facilities for experimentation, modelling can play a crucial role.
1 code implementation • 22 Aug 2019 • Christian Quirouette, Nada P. Younis, Micaela B. Reddy, Catherine A. A. Beauchemin
The MM herein represents the HRT as a one-dimensional track extending from the nose down to a depth of 30 cm, wherein stationary cells interact with the concentration of IAV which move along within the PCF.