no code implementations • 23 Aug 2023 • Okyaz Eminaga, Mahmoud Abbas, Christian Kunder, Yuri Tolkach, Ryan Han, James D. Brooks, Rosalie Nolley, Axel Semjonow, Martin Boegemann, Robert West, Jin Long, Richard Fan, Olaf Bettendorf
Adjusting the decision threshold for the secondary Gleason pattern from 5% to 10% improved the concordance level between pathologists and vPatho for tumor grading on prostatectomy specimens (kappa from 0. 44 to 0. 64).
1 code implementation • Medical Image Analysis 2021 • Rewa R. Sood, Wei Shao, Christian Kunder, Nikola C. Teslovich, Jeffrey B. Wang, Simon J.C. Soerensen, Nikhil Madhuripan, Anugayathri Jawahar, James D. Brooks, Pejman Ghanouni, Richard E. Fan, Geoffrey A. Sonn, Mirabela Rusu
Improvement in cancer detection on MRI is essential to reducing this variability and maximizing the clinical utility of MRI.
no code implementations • 21 Oct 2019 • Okyaz Eminaga, Mahmood Abbas, Yuri Tolkach, Rosalie Nolley, Christian Kunder, Axel Semjonow, Martin Boegemann
Histopathology is a reflection of the molecular changes and provides prognostic phenotypes representing the disease progression.
no code implementations • 11 Oct 2019 • Okyaz Eminaga, Yuri Tolkach, Christian Kunder, Mahmood Abbas, Ryan Han, Rosalie Nolley, Axel Semjonow, Martin Boegemann, Sebastian Huss, Andreas Loening, Robert West, Geoffrey Sonn, Richard Fan, Olaf Bettendorf, James Brook, Daniel Rubin
For case usage, these models were applied for the annotation tasks in clinician-oriented pathology reports for prostatectomy specimens.
no code implementations • 24 Aug 2019 • Okyaz Eminaga, Mahmoud Abbas, Christian Kunder, Andreas M. Loening, Jeanne Shen, James D. Brooks, Curtis P. Langlotz, Daniel L. Rubin
A well-fitted PlexusNet-based model delivered comparable classification performance (AUC: 0. 963) in distinguishing prostate cancer from healthy tissues, although it was at least 23 times smaller, had a better model calibration and clinical utility than the comparison models.