Phenotypic variation modulates the growth dynamics and response to radiotherapy of solid tumours under normoxia and hypoxia

no code implementations • 14 Jan 2021 • Giulia L. Celora, Helen M. Byrne, Christos Zois, Panos G. Kevrekidis

We use a combination of numerical and analytical techniques to quantify how under physiological oxygen levels the cells evolve to a differentiated phenotype and under low oxygen level (i. e., hypoxia) they de-differentiate.