no code implementations • 13 Jan 2024 • Shirui Bian, Ruisong Zhou, Wei Lin, Chunhe Li
Although the weighted summation of the Gaussian approximation (WSGA) approach has been proposed for quantifying the energy landscape in multistable systems by solving the diffusion equation approximately from moment equations, we are still lacking an accurate approach for quantifying the energy landscape of the periodic oscillatory systems.
no code implementations • 22 May 2023 • Zihao Chen, Jia Lu, Xing-Ming Zhao, Haiyang Yu, Chunhe Li
Our results revealed the underlying mechanism for intermediate cell states governing the CAC, and identified new potential drug combinations to induce cancer adipogenesis.
no code implementations • 12 Sep 2022 • Leijun Ye, Chunhe Li
The kinetic transition path identified by the minimum action path approach reveals that the spontaneous state serves as an intermediate state during the switch between the two memory states, the memory stored in the cortical area with higher hierarchy is more stable, and information flow follows the direction of hierarchical structure.
