no code implementations • 7 Oct 2022 • Juan Diaz-Colunga, Abigail Skwara, Karna Gowda, Ramon Diaz-Uriarte, Mikhail Tikhonov, Djordje Bajic, Alvaro Sanchez
Yet, patterns of global epistasis, in which the fitness effect of a mutation is well-predicted by the fitness of its genetic background, may actually be of help in our efforts to reconstruct fitness landscapes and infer adaptive trajectories.