no code implementations • 19 Jul 2016 • Dong-Ho Park, Taegeun Song, Danh-Tai Hoang, Jin Xu, Junghyo Jo
By testing all possible motifs governing the interactions of these three cell types, we found that a unique set of positive/negative intra-islet interactions between different islet cell types functions not only to reduce the superficially wasteful zero-sum action of glucagon and insulin but also to enhance/suppress the synchronization of hormone secretions between islets under high/normal glucose conditions.
