1 code implementation • 9 May 2022 • Domenic P. J. Germano, Stuart T. Johnston, Edmund J. Crampin, James M. Osborne
We also demonstrate the model's robustness under tissue renewal, cell migration and cell removal.
no code implementations • 13 Feb 2019 • Hilary Hunt, Agne Tilunaite, Greg Bass, Christian Soeller, H. Llewelyn Roderick, Vijay Rajagopal, Edmund J. Crampin
When coupled to a model of downstream transcription factor (NFAT) activation, we demonstrate that there is a high correspondence between the Ca transient duty cycle and the proportion of activated NFAT in the nucleus.
1 code implementation • 12 Jun 2018 • Michael Pan, Peter J. Gawthrop, Kenneth Tran, Joseph Cursons, Edmund J. Crampin
Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell membranes.
Biomolecules
no code implementations • 21 Jul 2015 • David M. Budden, Edmund J. Crampin
With the wealth of high-throughput sequencing data generated by recent large-scale consortia, predictive gene expression modelling has become an important tool for integrative analysis of transcriptomic and epigenetic data.