PointIso: Point Cloud Based Deep Learning Model for Detecting Arbitrary-Precision Peptide Features in LC-MS Map through Attention Based Segmentation

1 code implementation • 15 Sep 2020 • Fatema Tuz Zohora, M Ziaur Rahman, Ngoc Hieu Tran, Lei Xin, Baozhen Shan, Ming Li

A promising technique of discovering disease biomarkers is to measure the relative protein abundance in multiple biofluid samples through liquid chromatography with tandem mass spectrometry (LC-MS/MS) based quantitative proteomics.

DeepIso: A Deep Learning Model for Peptide Feature Detection

no code implementations • 9 Dec 2017 • Fatema Tuz Zohora, Ngoc Hieu Tran, Xianglilan Zhang, Lei Xin, Baozhen Shan, Ming Li

In this paper we propose a novel deep learning based model, DeepIso, that uses Convolutional Neural Networks (CNNs) to scan an LC-MS map to detect peptide features and estimate their abundance.

Drug Discovery Specificity