no code implementations • 3 Jul 2023 • Mrinal Pandey, Young Joon Suh, Minha Kim, Hannah Jane Davis, Jeffrey E Segall, Mingming Wu
Although the effects of tension within 3D extracellular matrices on tumor growth and invasion are well established, the role of compression in tumor mechanics and invasion is largely unexplored.
no code implementations • 29 Sep 2021 • Young Joon Suh, Mrinal Pandey, Jeffrey E Segall, Mingming Wu
Previously, we observed that single breast tumor cells (MDA-MB-231 cell line) embedded within a 3D collagen matrix displayed enhanced motility but no discernible chemotaxis in the presence of linear EGF gradients using a microfluidic platform.
