1 code implementation • 26 Sep 2022 • Gerardo Chowell, Sushma Dahal, Yuganthi R. Liyanage, Amna Tariq, Necibe Tuncer
We show that the lack of structural identifiability may be remedied by incorporating additional observations from different model states, assuming that the system's initial conditions are known, using prior information to fix some parameters involved in parameter correlations, or modifying the model based on existing parameter correlations.
no code implementations • 22 Nov 2021 • Hayriye Gulbudak, Zhuolin Qu, Fabio Milner, Necibe Tuncer
We then use SA for these immuno-epidemiological models to investigate the impact of immunological parameters on population-level disease dynamics such as basic reproduction number, final size of the epidemic or the infectiousness at different phases of an outbreak.