Search Results for author: Nicholas G Parker

Found 3 papers, 0 papers with code

An introduction to the mathematical modelling of iPSCs

no code implementations29 Oct 2020 Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Majlinda Lako, Nicholas G Parker, Anvar Shukurov

The aim of this chapter is to convey the importance and usefulness of mathematical modelling as a tool to achieve a deeper understanding of stem cell biology.

OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions

no code implementations20 Apr 2020 Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Majlinda Lako, R A Barrio, A W Baggaley, Nicholas G Parker, Anvar Shukurov

The improved in-vitro regulation of human embryonic stem cell (hESC) pluripotency and differentiation trajectories is required for their promising clinical applications.

Seeding hESCs to achieve optimal colony clonality

no code implementations16 Apr 2019 Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Sanja Bojic, Alex Laude, Majlina Lako, Nicholas G Parker, Anvar Shukurov

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have promising clinical applications which often rely on clonally-homogeneous cell populations.

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