no code implementations • 29 Oct 2020 • Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Majlinda Lako, Nicholas G Parker, Anvar Shukurov
The aim of this chapter is to convey the importance and usefulness of mathematical modelling as a tool to achieve a deeper understanding of stem cell biology.
no code implementations • 20 Apr 2020 • Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Majlinda Lako, R A Barrio, A W Baggaley, Nicholas G Parker, Anvar Shukurov
The improved in-vitro regulation of human embryonic stem cell (hESC) pluripotency and differentiation trajectories is required for their promising clinical applications.
no code implementations • 16 Apr 2019 • Laura E Wadkin, Sirio Orozco-Fuentes, Irina Neganova, Sanja Bojic, Alex Laude, Majlina Lako, Nicholas G Parker, Anvar Shukurov
Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have promising clinical applications which often rely on clonally-homogeneous cell populations.