Computationally repurposed drugs and natural products against RNA dependent RNA polymerase as potential COVID-19 therapies

no code implementations • 29 Nov 2020 • Sakshi Piplani, Puneet Singh, David A. Winkler, Nikolai Petrovsky

For fast development of COVID-19, it is only feasible to use drugs (off label use) or approved natural products that are already registered or been assessed for safety in previous human trials.

Computational screening of repurposed drugs and natural products against SARS-Cov-2 main protease (Mpro) as potential COVID-19 therapies

no code implementations • 1 Sep 2020 • Sakshi Piplani, Puneet Singh, Nikolai Petrovsky, David A. Winkler

We show how the resulting shortlist of candidates with strongest binding affinities is highly enriched in compounds that have been independently identified as potential antivirals against COVID-19.

Analyzing Newspaper Crime Reports for Identification of Safe Transit Paths

no code implementations • NAACL 2015 • Vasu Sharma, Rajat Kulshreshtha, Puneet Singh, Nishant Agrawal, Akshay Kumar