Search Results for author: Rui D. M. Travasso

Found 5 papers, 5 papers with code

The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction

3 code implementations Communications Biology 2023 Soraia Melo, Pilar Guerrero, Maurício Moreira Soares, José Rafael Bordin, Fátima Carneiro, Patrícia Carneiro, Maria Beatriz Dias, João Carvalho, Joana Figueiredo, Raquel Seruca, Rui D. M. Travasso

Germline mutations of E-cadherin cause Hereditary Diffuse Gastric Cancer (HDGC), a highly invasive cancer syndrome characterised by the occurrence of diffuse-type gastric carcinoma and lobular breast cancer.

Adhesion modulates cell morphology and migration within dense fibrous networks

1 code implementation Journal of Physics: Condensed Matter 2020 Maurício Moreira-Soares, Susana P. Cunha, José Rafael Bordin, Rui D. M. Travasso

With this purpose we have measured in our simulation the cell's velocity and quantified its morphology as a function of the fibre density and of its adhesiveness to the matrix fibres.

Angiogenic Factors produced by Hypoxic Cells are a leading driver of Anastomoses in Sprouting Angiogenesis---a computational study

1 code implementation12 Jun 2018 Maurício Moreira-Soares, Rita Coimbra, Luís Rebelo, João Carvalho, Rui D. M. Travasso

We demonstrate that this increased production of angiogenic factors by hypoxic cells is able to promote vessel anastomoses events in both 2D and 3D.

Biological Physics Soft Condensed Matter Tissues and Organs

Cannot find the paper you are looking for? You can Submit a new open access paper.