G4-Attention: Deep Learning Model with Attention for predicting DNA G-Quadruplexes

no code implementations • 5 Mar 2024 • Shrimon Mukherjee, Pulakesh Pramanik, Partha Basuchowdhuri, Santanu Bhattacharya

G-Quadruplexes are the four-stranded non-canonical nucleic acid secondary structures, formed by the stacking arrangement of the guanine tetramers.

Deep Graph Convolutional Network and LSTM based approach for predicting drug-target binding affinity

1 code implementation • 18 Jan 2022 • Shrimon Mukherjee, Madhusudan Ghosh, Partha Basuchowdhuri

We use our novel architecture to predict a Combined Score (calculated using Davis and KIBA score) of 2, 304 FDA-approved drugs against 5 viral proteins.

Drug Discovery