Search Results for author: Umberto Lupo

Found 5 papers, 4 papers with code

Pairing interacting protein sequences using masked language modeling

1 code implementation14 Aug 2023 Umberto Lupo, Damiano Sgarbossa, Anne-Florence Bitbol

We introduce a method called DiffPALM that solves it by exploiting the ability of MSA Transformer to fill in masked amino acids in multiple sequence alignments using the surrounding context.

Masked Language Modeling Protein Language Model

Impact of phylogeny on structural contact inference from protein sequence data

no code implementations26 Sep 2022 Nicola Dietler, Umberto Lupo, Anne-Florence Bitbol

Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins.

Protein language models trained on multiple sequence alignments learn phylogenetic relationships

1 code implementation29 Mar 2022 Umberto Lupo, Damiano Sgarbossa, Anne-Florence Bitbol

Simple combinations of MSA Transformer's row attentions have led to state-of-the-art unsupervised structural contact prediction.

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