1 code implementation • 14 Aug 2023 • Umberto Lupo, Damiano Sgarbossa, Anne-Florence Bitbol
We introduce a method called DiffPALM that solves it by exploiting the ability of MSA Transformer to fill in masked amino acids in multiple sequence alignments using the surrounding context.
no code implementations • 26 Sep 2022 • Nicola Dietler, Umberto Lupo, Anne-Florence Bitbol
Local and global inference methods have been developed to infer structural contacts from multiple sequence alignments of homologous proteins.
1 code implementation • 14 Apr 2022 • Damiano Sgarbossa, Umberto Lupo, Anne-Florence Bitbol
Moreover, for small protein families, our generation method based on MSA Transformer outperforms Potts models.
1 code implementation • 29 Mar 2022 • Umberto Lupo, Damiano Sgarbossa, Anne-Florence Bitbol
Simple combinations of MSA Transformer's row attentions have led to state-of-the-art unsupervised structural contact prediction.
1 code implementation • NeurIPS Workshop TDA_and_Beyond 2020 • Guillaume Tauzin, Umberto Lupo, Lewis Tunstall, Julian Burella Pérez, Matteo Caorsi, Wojciech Reise, Anibal Medina-Mardones, Alberto Dassatti, Kathryn Hess
We introduce giotto-tda, a Python library that integrates high-performance topological data analysis with machine learning via a scikit-learn-compatible API and state-of-the-art C++ implementations.