General Chemical Reaction Network Theory for Olfactory Sensing Based on G-Protein-Coupled Receptors : Elucidation of Odorant Mixture Effects and Agonist-Synergist Threshold

no code implementations • 23 Aug 2023 • Won Kyu Kim, Kiri Choi, Changbong Hyeon, Seogjoo J. Jang

A unique feature of the theory is the definition of an odor activity vector consisting of strengths of odorant-induced signals from ORs relative to those due to background G-protein activity in the absence of odorants.

Polymer brush-induced depletion interactions and clustering of membrane proteins

no code implementations • 25 Feb 2021 • Anvy Moly Tom, Won Kyu Kim, Changbong Hyeon

We investigate the effect of mobile polymer brushes on proteins embedded in biological membranes by employing both Asakura-Oosawa type of theoretical model and coarse-grained molecular dynamics simulations.

Soft Condensed Matter Biological Physics Biomolecules