S2Looking is a building change detection dataset that contains large-scale side-looking satellite images captured at varying off-nadir angles. The S2Looking dataset consists of 5,000 registered bitemporal image pairs (size of 1024*1024, 0.5 ~ 0.8 m/pixel) of rural areas throughout the world and more than 65,920 annotated change instances. We provide two label maps to separately indicate the newly built and demolished building regions for each sample in the dataset. We establish a benchmark task based on this dataset, i.e., identifying the pixel-level building changes in the bi-temporal images.