Architecture of Data Anomaly Detection-Enhanced Decentralized Expert System for Early-Stage Alzheimer's Disease Prediction

1 Nov 2023  ·  Stefan Kambiz Behfar, Qumars Behfar, Marzie Hosseinpour ·

Alzheimer's Disease is a global health challenge that requires early and accurate detection to improve patient outcomes. Magnetic Resonance Imaging (MRI) holds significant diagnostic potential, but its effective analysis remains a formidable task. This study introduces a groundbreaking decentralized expert system that cleverly combines blockchain technology with Artificial Intelligence (AI) to integrate robust anomaly detection for patient-submitted data. Traditional diagnostic methods often lead to delayed and imprecise predictions, especially in the early stages of the disease. Centralized data repositories struggle to manage the immense volumes of MRI data, and persistent privacy concerns hinder collaborative efforts. Our innovative solution harnesses decentralization to protect data integrity and patient privacy, facilitated by blockchain technology. It not only emphasizes AI-driven MRI analysis but also incorporates a sophisticated data anomaly detection architecture. These mechanisms scrutinize patient-contributed data for various issues, including data quality problems and atypical findings within MRI images. Conducting an exhaustive check of MRI image correctness and quality directly on the blockchain is impractical due to computational complexity and cost constraints. Typically, such checks are performed off-chain, and the blockchain securely records the results. This comprehensive approach empowers our decentralized app to provide more precise early-stage Alzheimer's Disease predictions. By merging the strengths of blockchain, AI, and anomaly detection, our system represents a pioneering step towards revolutionizing disease diagnostics.

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