EM-NET: Centerline-Aware Mitochondria Segmentation in EM Images via Hierarchical View-Ensemble Convolutional Network

30 Nov 2019  ·  Zhimin Yuan, Jiajin Yi, Zhengrong Luo, Zhongdao Jia, Jialin Peng ·

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives. Besides, the need for labor intensive annotations of large 3D dataset and huge memory overhead by 3D models are also major limitations. To address these problems, we introduce a multi-task network named EM-Net, which includes an auxiliary centerline detection task to account for shape information of mitochondria represented by centerline. Therefore, the centerline detection sub-network is able to enhance the accuracy and robustness of segmentation task, especially when only a small set of annotated data are available. To achieve a light-weight 3D network, we introduce a novel hierarchical view-ensemble convolution module to reduce number of parameters, and facilitate multi-view information aggregation.Validations on public benchmark showed state-of-the-art performance by EM-Net. Even with significantly reduced training data, our method still showed quite promising results.

PDF Abstract
No code implementations yet. Submit your code now

Datasets


  Add Datasets introduced or used in this paper

Results from the Paper


  Submit results from this paper to get state-of-the-art GitHub badges and help the community compare results to other papers.

Methods