Search Results for author: Paul M. Thompson

Found 28 papers, 3 papers with code

DenseNet and Support Vector Machine classifications of major depressive disorder using vertex-wise cortical features

no code implementations18 Nov 2023 Vladimir Belov, Tracy Erwin-Grabner, Ling-Li Zeng, Christopher R. K. Ching, Andre Aleman, Alyssa R. Amod, Zeynep Basgoze, Francesco Benedetti, Bianca Besteher, Katharina Brosch, Robin Bülow, Romain Colle, Colm G. Connolly, Emmanuelle Corruble, Baptiste Couvy-Duchesne, Kathryn Cullen, Udo Dannlowski, Christopher G. Davey, Annemiek Dols, Jan Ernsting, Jennifer W. Evans, Lukas Fisch, Paola Fuentes-Claramonte, Ali Saffet Gonul, Ian H. Gotlib, Hans J. Grabe, Nynke A. Groenewold, Dominik Grotegerd, Tim Hahn, J. Paul Hamilton, Laura K. M. Han, Ben J Harrison, Tiffany C. Ho, Neda Jahanshad, Alec J. Jamieson, Andriana Karuk, Tilo Kircher, Bonnie Klimes-Dougan, Sheri-Michelle Koopowitz, Thomas Lancaster, Ramona Leenings, Meng Li, David E. J. Linden, Frank P. MacMaster, David M. A. Mehler, Susanne Meinert, Elisa Melloni, Bryon A. Mueller, Benson Mwangi, Igor Nenadić, Amar Ojha, Yasumasa Okamoto, Mardien L. Oudega, Brenda W. J. H. Penninx, Sara Poletti, Edith Pomarol-Clotet, Maria J. Portella, Elena Pozzi, Joaquim Radua, Elena Rodríguez-Cano, Matthew D. Sacchet, Raymond Salvador, Anouk Schrantee, Kang Sim, Jair C. Soares, Aleix Solanes, Dan J. Stein, Frederike Stein, Aleks Stolicyn, Sophia I. Thomopoulos, Yara J. Toenders, Aslihan Uyar-Demir, Eduard Vieta, Yolanda Vives-Gilabert, Henry Völzke, Martin Walter, Heather C. Whalley, Sarah Whittle, Nils Winter, Katharina Wittfeld, Margaret J. Wright, Mon-Ju Wu, Tony T. Yang, Carlos Zarate, Dick J. Veltman, Lianne Schmaal, Paul M. Thompson, Roberto Goya-Maldonado

Based on the hypothesis that integration of vertex-wise cortical features can improve classification performance, we evaluated the classification of a DenseNet and a Support Vector Machine (SVM), with the expectation that the former would outperform the latter.

Incomplete Multimodal Learning for Complex Brain Disorders Prediction

no code implementations25 May 2023 Reza Shirkavand, Liang Zhan, Heng Huang, Li Shen, Paul M. Thompson

Especially in studies of brain diseases, research cohorts may include both neuroimaging data and genetic data, but for practical clinical diagnosis, we often need to make disease predictions only based on neuroimages.

Data Integration

A Surface-Based Federated Chow Test Model for Integrating APOE Status, Tau Deposition Measure, and Hippocampal Surface Morphometry

no code implementations31 Mar 2023 Jianfeng Wu, Yi Su, Yanxi Chen, Wenhui Zhu, Eric M. Reiman, Richard J. Caselli, Kewei Chen, Paul M. Thompson, Junwen Wang, Yalin Wang

Objective: To build a surface-based model to 1) detect differences between APOE subgroups in patterns of tau deposition and hippocampal atrophy, and 2) use the extracted surface-based features to predict cognitive decline.

Few-Shot Classification of Autism Spectrum Disorder using Site-Agnostic Meta-Learning and Brain MRI

no code implementations14 Mar 2023 Nikhil J. Dhinagar, Vignesh Santhalingam, Katherine E. Lawrence, Emily Laltoo, Paul M. Thompson

Inspired by the effectiveness of meta-learning for optimizing a model across multiple tasks, here we propose a framework to adapt it to learn across multiple sites.

Meta-Learning Transfer Learning

Efficiently Training Vision Transformers on Structural MRI Scans for Alzheimer's Disease Detection

no code implementations14 Mar 2023 Nikhil J. Dhinagar, Sophia I. Thomopoulos, Emily Laltoo, Paul M. Thompson

In our experiments, two vision transformer architecture variants achieved an AUC of 0. 987 for sex and 0. 892 for AD classification, respectively.

Alzheimer's Disease Detection Data Augmentation

Curriculum Based Multi-Task Learning for Parkinson's Disease Detection

no code implementations27 Feb 2023 Nikhil J. Dhinagar, Conor Owens-Walton, Emily Laltoo, Christina P. Boyle, Yao-Liang Chen, Philip Cook, Corey McMillan, Chih-Chien Tsai, J-J Wang, Yih-Ru Wu, Ysbrand van der Werf, Paul M. Thompson

There is great interest in developing radiological classifiers for diagnosis, staging, and predictive modeling in progressive diseases such as Parkinson's disease (PD), a neurodegenerative disease that is difficult to detect in its early stages.

Multi-Task Learning

Improved Prediction of Beta-Amyloid and Tau Burden Using Hippocampal Surface Multivariate Morphometry Statistics and Sparse Coding

no code implementations28 Oct 2022 Jianfeng Wu, Yi Su, Wenhui Zhu, Negar Jalili Mallak, Natasha Lepore, Eric M. Reiman, Richard J. Caselli, Paul M. Thompson, Kewei Chen, Yalin Wang

Experimental results suggest that amyloid/tau measurements predicted with our PASCP-MP representations are closer to the real values than the measures derived from other approaches, such as hippocampal surface area, volume, and shape morphometry features based on spherical harmonics (SPHARM).

Secure & Private Federated Neuroimaging

no code implementations11 May 2022 Dimitris Stripelis, Umang Gupta, Hamza Saleem, Nikhil Dhinagar, Tanmay Ghai, Rafael Chrysovalantis Anastasiou, Armaghan Asghar, Greg Ver Steeg, Srivatsan Ravi, Muhammad Naveed, Paul M. Thompson, Jose Luis Ambite

Each site trains the neural network over its private data for some time, then shares the neural network parameters (i. e., weights, gradients) with a Federation Controller, which in turn aggregates the local models, sends the resulting community model back to each site, and the process repeats.

Federated Learning

Secure Neuroimaging Analysis using Federated Learning with Homomorphic Encryption

no code implementations7 Aug 2021 Dimitris Stripelis, Hamza Saleem, Tanmay Ghai, Nikhil Dhinagar, Umang Gupta, Chrysovalantis Anastasiou, Greg Ver Steeg, Srivatsan Ravi, Muhammad Naveed, Paul M. Thompson, Jose Luis Ambite

Federated learning (FL) enables distributed computation of machine learning models over various disparate, remote data sources, without requiring to transfer any individual data to a centralized location.

Benchmarking Federated Learning

Membership Inference Attacks on Deep Regression Models for Neuroimaging

no code implementations6 May 2021 Umang Gupta, Dimitris Stripelis, Pradeep K. Lam, Paul M. Thompson, José Luis Ambite, Greg Ver Steeg

In particular, we show that it is possible to infer if a sample was used to train the model given only access to the model prediction (black-box) or access to the model itself (white-box) and some leaked samples from the training data distribution.

Federated Learning regression

3D Grid-Attention Networks for Interpretable Age and Alzheimer's Disease Prediction from Structural MRI

no code implementations18 Nov 2020 Pradeep Lam, Alyssa H. Zhu, Iyad Ba Gari, Neda Jahanshad, Paul M. Thompson

Building on a 3D convolutional neural network, we added two attention modules at different layers of abstraction, so that features learned are spatially related to the global features for the task.

Disease Prediction

Scanner Invariant Representations for Diffusion MRI Harmonization

no code implementations10 Apr 2019 Daniel Moyer, Greg Ver Steeg, Chantal M. W. Tax, Paul M. Thompson

Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation.

Fairness Image Reconstruction

Measures of Tractography Convergence

no code implementations12 Jun 2018 Daniel Moyer, Paul M. Thompson, Greg Ver Steeg

In the present work, we use information theory to understand the empirical convergence rate of tractography, a widely-used approach to reconstruct anatomical fiber pathways in the living brain.

A Restaurant Process Mixture Model for Connectivity Based Parcellation of the Cortex

1 code implementation2 Mar 2017 Daniel Moyer, Boris A. Gutman, Neda Jahanshad, Paul M. Thompson

One of the primary objectives of human brain mapping is the division of the cortical surface into functionally distinct regions, i. e. parcellation.

An Empirical Study of Continuous Connectivity Degree Sequence Equivalents

no code implementations18 Nov 2016 Daniel Moyer, Boris A. Gutman, Joshua Faskowitz, Neda Jahanshad, Paul M. Thompson

In the present work we demonstrate the use of a parcellation free connectivity model based on Poisson point processes.

Point Processes

Large-scale Collaborative Imaging Genetics Studies of Risk Genetic Factors for Alzheimer's Disease Across Multiple Institutions

no code implementations19 Aug 2016 Qingyang Li, Tao Yang, Liang Zhan, Derrek Paul Hibar, Neda Jahanshad, Yalin Wang, Jieping Ye, Paul M. Thompson, Jie Wang

To the best of our knowledge, this is the first successful run of the computationally intensive model selection procedure to learn a consistent model across different institutions without compromising their privacy while ranking the SNPs that may collectively affect AD.

Model Selection

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