Vagus nerve manipulation and microglial plasticity in the prenatal brain

no code implementations • 19 Dec 2022 • Marc Courchesne, Colin Wakefield, Karen Nygard, Patrick Burns, Gilles Fecteau, Andre Desrochers, Mingju Cao, Martin G. Frasch

The efferent and afferent effects of the vagus nerve on the developing brain have remained enigmatic.

The neonatal sepsis is diminished by cervical vagus nerve stimulation and tracked non-invasively by ECG: a preliminary report in the piglet model

no code implementations • 10 Feb 2020 • Aude Castel, Patrick Burns, Colin Wakefield, Keven. J. Jean, Yael S. Frank, Mingju Cao, Andre Desrochers, Gilles Fecteau, Christophe Faure, Christophe L. Herry, Martin G. Frasch

We evaluated the effect of vagus nerve stimulation (VNS) on vagus nerve electroneurogram (VENG) and the systemic inflammatory response induced by a high dose of LPS in neonatal piglets to mimic late-onset neonatal sepsis.

Heart Rate Variability