Bridging from single to collective cell migration: A review of models and links to experiments

no code implementations • 21 Nov 2020 • Andreas Buttenschön, Leah Edelstein-Keshet

Mathematical and computational models can assist in gaining an understanding of cell behavior at many levels of organization.

Adhesion-driven patterns in a calcium-dependent model of cancer cell movement

no code implementations • 1 Mar 2020 • Katerina Kaouri, Vasiliki Bitsouni, Andreas Buttenschön, Rüdiger Thul

The cancer cell density exhibits travelling fronts and complex spatial patterns arising from an adhesion-driven instability (ADI).

Cell size, mechanical tension, and GTPase signaling in the Single Cell

no code implementations • 28 Aug 2019 • Andreas Buttenschön, Yue Liu, Leah Edelstein-Keshet

We further consider the feedback between mechanical tension, GTPase activation, and cell deformation in both static, growing, shrinking, and moving cells.