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Found 4 papers, 3 papers with code
Standardised workflow for mass spectrometry-based single-cell proteomics data processing and analysis using the scp package
Our main steps are quality control on the feature and cell level, aggregation of the raw data into peptides and proteins, normalisation and batch correction.
Revisiting the thorny issue of missing values in single-cell proteomics
While the field is still actively debating on the best practices, the challenge increased with the emergence of mass spectrometry-based single-cell proteomics and the dramatic increase in missing values.
The current state of single-cell proteomics data analysis
Sound data analysis is essential to retrieve meaningful biological information from single-cell proteomics experiments.
Initial recommendations for performing, benchmarking, and reporting single-cell proteomics experiments
Analyzing proteins from single cells by tandem mass spectrometry (MS) has become technically feasible.
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